Case Report
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jul 6, 2024; 12(19): 3985-3994
Published online Jul 6, 2024. doi: 10.12998/wjcc.v12.i19.3985
Myeloid sarcoma with maxillary gingival swelling as the initial symptom: A case report and review of literature
Shu-Han Li, Cai-Xiu Yang, Xiao-Ming Xing, Xiang-Ru Gao, Zhao-Yu Lu, Qiu-Xia Ji
Shu-Han Li, Cai-Xiu Yang, Xiang-Ru Gao, Zhao-Yu Lu, Qiu-Xia Ji, Department of Periodontology, The Affiliated Hospital of Qingdao University, Qingdao 266003, Shandong Province, China
Shu-Han Li, Cai-Xiu Yang, Xiang-Ru Gao, Zhao-Yu Lu, Qiu-Xia Ji, Department of Periodontology, School of Stomatology of Qingdao University, Qingdao 266000, Shandong Province, China
Xiao-Ming Xing, Department of Pathology, The Affiliated Hospital of Qingdao University, Qingdao 266003, Shandong Province, China
Author contributions: Li SH contributed to conception, design, drafted, and critically revised the manuscript; Yang CX and Xing XM contributed to acquisition, and drafted the manuscript; Gao XR and Lu ZY contributed to acquisition, analysis, and drafted the manuscript; Ji QX contributed to conception, design, acquisition, analysis, interpretation, and critically revised the manuscript; all authors gave their final approval and agree to be accountable for all aspects of the work.
Supported by The Natural Science Foundation of Shandong Province, No. ZR2019MH003.
Informed consent statement: The involved person gave informed consent prior to study inclusion.
Conflict-of-interest statement: The authors have stated explicitly that there are no conflicts of interest in connection with this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Qiu-Xia Ji, Doctor, Professor, Department of Periodontology, The Affiliated Hospital of Qingdao University, No. 16 Jiangsu Road, Qing dao 266003, Shandong Province, China. jqx_1@qdu.edu.cn
Received: March 3, 2024
Revised: April 25, 2024
Accepted: May 7, 2024
Published online: July 6, 2024
Processing time: 118 Days and 3.1 Hours
Core Tip

Core Tip: We report a rare case of myeloid sarcoma (MS) with maxillary gingival swelling as the initial symptom. In this case, histopathological and immunohistochemical analyses showed diffuse infiltration of myeloperoxidase-positive neoplastic cells with 80% Ki-67 staining, indicating MS. Flow cytometry revealed a predominance of granulocytes without distinct B-cell or T-cell markers, supporting the diagnosis. Absence of CD20 and CD3 markers lessened lymphoma likelihood, confirming the lesion's hematopoietic nature.