Published online Jul 6, 2024. doi: 10.12998/wjcc.v12.i19.3985
Revised: April 25, 2024
Accepted: May 7, 2024
Published online: July 6, 2024
Processing time: 118 Days and 3.1 Hours
Myeloid sarcoma (MS), also referred to as granulocytic sarcoma or chloroma, is a rare type of extramedullary malignant tumor. MS comprises primitive granu
The present study reported the case of MS with gingival swelling in the maxillary region, with aleukemic presentation in a 32-year-old male patient. Following two courses of chemotherapy, computed tomography of the region demonstrated complete clearance of the tumor. At the 12-month follow-up appointment, the patient was in a stable condition with the absence of progression. The etiology, clinical features, diagnosis, and relevant treatment of MS are discussed in the present study.
Diagnosis of MS may be confirmed following histological and immunohistoche
Core Tip: We report a rare case of myeloid sarcoma (MS) with maxillary gingival swelling as the initial symptom. In this case, histopathological and immunohistochemical analyses showed diffuse infiltration of myeloperoxidase-positive neoplastic cells with 80% Ki-67 staining, indicating MS. Flow cytometry revealed a predominance of granulocytes without distinct B-cell or T-cell markers, supporting the diagnosis. Absence of CD20 and CD3 markers lessened lymphoma likelihood, confirming the lesion's hematopoietic nature.