Retrospective Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jun 16, 2024; 12(17): 3027-3034
Published online Jun 16, 2024. doi: 10.12998/wjcc.v12.i17.3027
Effect of Luhong formula on the cardiac rehabilitation of patients with chronic heart failure
Ji-Jie Xu, Jian Dai, Qi-Hai Xie, Pei-Chao Du, Cha Li, Hua Zhou
Ji-Jie Xu, Jian Dai, Qi-Hai Xie, Pei-Chao Du, Cha Li, Hua Zhou, Department of Cardiology & Cardiovascular Research Institute, Shanghai Baoshan District Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai 201999, China
Author contributions: Xu JJ proposed the concept of this study; Xu JJ, Dai J, Xie QH and Zhou H contributed to data collection; Xu JJ drafted the first draft; Xu JJ, Dai J and Zhou H contributed to the formal analysis of this study; Du PC and Li C conducted guidance research, methodology, and visualization; all authors participated in the study, validated the study, and jointly reviewed and edited the manuscript.
Supported by Science and Technology Commission of Shanghai Municipality, No. 21Y11920100; National Natural Science Foundation of China, No. 81904016; Baoshan District Health Commission, No. BSZK-2023-Z02.
Institutional review board statement: This study was approved by the Ethic Committee of Shanghai Baoshan District Hospital of Integrated Traditional Chinese and Western Medicine (Approval No. 202119).
Informed consent statement: All the study subjects provided informed consent.
Conflict-of-interest statement: Dr. Xu has nothing to disclose.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ji-Jie Xu, PhD, Doctor, Department of Cardiology & Cardiovascular Research Institute, Shanghai Baoshan District Hospital of Integrated Traditional Chinese and Western Medicine, No. 181 Youyi Road, Baoshan District, Shanghai 201999, China. adamxu628@163.com
Received: March 1, 2024
Revised: April 22, 2024
Accepted: April 24, 2024
Published online: June 16, 2024
Processing time: 95 Days and 8.3 Hours
Core Tip

Core Tip: Traditional Chinese medicine (TCM) has great potential and clinical value in the treatment of chronic heart failure (CHF). This study analyzed the clinical efficacy of Luhong formula in the treatment of patients with CHF in terms of its curative effects on TCM syndromes and cardiac function, cardiopulmonary function (CPF), echocardiographic indexes, and prognosis. Luhong Formula showed a significantly better therapeutic effect on cardiac rehabilitation for CHF than perindopril, specifically in improving CPF and prognosis. The findings demonstrate the potential of Luhong formula as an effective TCM-based treatment option that can be integrated into cardiac rehabilitation strategies for CHF.