Published online Jun 16, 2024. doi: 10.12998/wjcc.v12.i17.3027
Revised: April 22, 2024
Accepted: April 24, 2024
Published online: June 16, 2024
Processing time: 95 Days and 8.3 Hours
Current treatments for chronic heart failure (CHF) are therapeutically ineffective. The optimization of treatments for this disease needs to be explored and analyzed.
To analyze the effect of using Luhong Formula in the cardiac rehabilitation of patients with CHF and its influence on cardiopulmonary function (CPF) and prognosis.
In total, 160 patients with CHF admitted between June 2022 and June 2023 were selected, including 75 receiving perindopril (control group) and 85 receiving Luhong Formula (research group). We conducted comparative analyses on the curative effects of traditional Chinese medicine (TCM) syndromes and cardiac function, CPF [oxygen consumption at the anaerobic threshold (VO2 AT) and at peak exercise (peak VO2)], echocardiographic indexes [left atrial volume index (LAVI), left ventricular muscle mass index (LVMI), left ventricular ejection fraction (LVEF)], and prognosis [major adverse cardiovascular events (MACEs) at 6 months follow-up].
The research group showed markedly higher curative effects of TCM syndromes and cardiac function than the control group. In addition, post-treatment VO2 AT, peak VO2, LVMI and LVEF in the research group were significantly higher, whereas LAVI was significantly lower, than those of the control group. Fur
Luhong Formula is more therapeutically effective than perindopril for the cardiac rehabilitation of patients with CHF, specifically in enhancing CPF and prognosis.
Core Tip: Traditional Chinese medicine (TCM) has great potential and clinical value in the treatment of chronic heart failure (CHF). This study analyzed the clinical efficacy of Luhong formula in the treatment of patients with CHF in terms of its curative effects on TCM syndromes and cardiac function, cardiopulmonary function (CPF), echocardiographic indexes, and prognosis. Luhong Formula showed a significantly better therapeutic effect on cardiac rehabilitation for CHF than perindopril, specifically in improving CPF and prognosis. The findings demonstrate the potential of Luhong formula as an effective TCM-based treatment option that can be integrated into cardiac rehabilitation strategies for CHF.