Retrospective Study
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Dec 26, 2023; 11(36): 8458-8474
Published online Dec 26, 2023. doi: 10.12998/wjcc.v11.i36.8458
Functional magnetic resonance imaging study of group independent components underpinning item responses to paranoid-depressive scale
Drozdstoy Stoyanov, Rositsa Paunova, Julian Dichev, Sevdalina Kandilarova, Vladimir Khorev, Semen Kurkin
Drozdstoy Stoyanov, Department of Psychiatry, Medical University Plovdiv, Plovdiv 4000, Bulgaria
Rositsa Paunova, Research Institute, Medical University, Plovdiv 4002, Bulgaria
Julian Dichev, Faculty of Medicine, Medical University, Plovdiv 4002, Bulgaria
Sevdalina Kandilarova, Department of Psychiatry and Medical Psychology, Medical University, Plovdiv 4002, Bulgaria
Vladimir Khorev, Semen Kurkin, Baltic Center for Artificial Intelligence and Neurotechnology, Immanuel Kant Baltic Federal University, Kaliningrad 236041, Russia
Author contributions: Stoyanov D designed the research study and wrote the manuscript; Stoyanov D and Kandilarova S performed the research; Paunova R, Kurkin S and Khorev V analyzed the data; all authors have read and approved the final manuscript.
Institutional review board statement: This study was reviewed and approved by the Ethics Committee of Medical University of Plovdiv.
Informed consent statement: All study participants or their legal guardian provided informed written consent about personal and medical data collection prior to study enrolment.
Conflict-of-interest statement: We have no financial relationships to disclose.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Drozdstoy Stoyanov, DSc, Full Professor, Department of Psychiatry, Medical University Plovdiv, Vassil Aprilov 15a, Plovdiv 4000, Bulgaria. drozdstoy.stoyanov@mu-plovdiv.bg
Received: September 26, 2023
Peer-review started: September 26, 2023
First decision: November 9, 2023
Revised: November 10, 2023
Accepted: December 5, 2023
Article in press: December 5, 2023
Published online: December 26, 2023
Core Tip

Core Tip: There have been identified five independent components, on the level of brain signals, which are significantly modulated by clinical diagnostic scales adapted to functional magnetic resonance imaging paradigm. Those results may help potentially to define patterns of activations which differ between patients with depression and patients with schizophrenia.