Retrospective Study
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Sep 16, 2023; 11(26): 6066-6072
Published online Sep 16, 2023. doi: 10.12998/wjcc.v11.i26.6066
Lyophilized recombinant human brain natriuretic peptide for chronic heart failure: Effects on cardiac function and inflammation
Feng Li, Hao Li, Rong Luo, Jia-Bao Pei, Xue-Ying Yu
Feng Li, Hao Li, Rong Luo, Jia-Bao Pei, Xue-Ying Yu, Department of Cardiovascular Internal Medicine, People's Hospital of Jieshou, Jieshou 236500, Anhui Province, China
Author contributions: Li F and Li H contributed equally to this work; Li F, Li H, Luo R, Pei JB, and Yu XY designed the research study; Li F, Li H, Pei JB, and Luo R performed the research; Yu XY and Li F contributed new reagents and analytic tools; Li F, Li H and Pei JB analyzed the data and wrote the manuscript; and all authors have read and approve the final manuscript.
Institutional review board statement: The study was reviewed and approved by the People's Hospital of Jieshou Institutional Review Board.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All authors have no conflicts of interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Feng Li, Associate Chief Physician, Master's Student, Department of Cardiovascular Internal Medicine, People's Hospital of Jieshou, No. 399 Renmin East Road, Jieshou 236500, Anhui Province, China. lff753159789@163.com
Received: April 24, 2023
Peer-review started: April 24, 2023
First decision: May 8, 2023
Revised: May 20, 2023
Accepted: August 3, 2023
Article in press: August 3, 2023
Published online: September 16, 2023
Processing time: 137 Days and 1.5 Hours
Core Tip

Core Tip: Lyophilized recombinant human brain natriuretic peptide therapy can improve heart function and reduce microinflammation in patients with chronic heart failure, which signifies its potential as a safe and effective treatment option.