Case Report
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. May 16, 2023; 11(14): 3248-3255
Published online May 16, 2023. doi: 10.12998/wjcc.v11.i14.3248
Diagnosis of tuberculous uveitis by the macrogenome of intraocular fluid: A case report and review of the literature
Yan-Kun Zhang, Yan Guan, Juan Zhao, Li-Fei Wang
Yan-Kun Zhang, Yan Guan, Department of Ophthalmology, Hebei Chest Hospital, Shijiazhuang 050047, Hebei Province, China
Juan Zhao, Department of Respiratory, Hebei Chest Hospital, Shijiazhuang 050047, Hebei Province, China
Li-Fei Wang, Department of Ophthalmology, Hebei Eye Hospital, Xingtai 050010, Hebei Province, China
Author contributions: Zhang YK contributed to design and drafting the manuscript; Guan Y, Zhao J and Wang LF contributed to case collection; and all authors approved the final version of the manuscript.
Supported by the Medical Science Research Project of Hebei Province, No. 20191029.
Informed consent statement: The patient signed an informed consent.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Li-Fei Wang, Chief Physician, Doctor, Department of Ophthalmology, Hebei Eye Hospital, No. 399 Quanbei East Street, Xingtai 050010, Hebei Province, China. 928246030@qq.com
Received: September 3, 2022
Peer-review started: September 3, 2022
First decision: February 14, 2023
Revised: February 28, 2023
Accepted: March 24, 2023
Article in press: March 24, 2023
Published online: May 16, 2023
Processing time: 174 Days and 3 Hours
Core Tip

Core Tip: Tuberculous uveitis caused by tuberculosis infection factors is common, but tuberculous uveitis caused by Mycobacterium tuberculosis found in intraocular fluid is rare. This report describes a 24-year-old pregnant patient who was diagnosed using tuberculosis Xpert and ophthalmologic multimodal imaging after 2 mo of anti-tuberculosis treatment and cesarean delivery of a healthy baby boy. Detection of intraocular infections can be performed by second-generation genetics. Folowing systemic treatment, the patient’s vision recovered.