Retrospective Study
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. May 16, 2023; 11(14): 3176-3186
Published online May 16, 2023. doi: 10.12998/wjcc.v11.i14.3176
Clinical features and prognostic factors in 49 patients with follicular lymphoma at a single center: A retrospective analysis
Hao Wu, Hui-Cong Sun, Gui-Fang Ouyang
Hao Wu, Gui-Fang Ouyang, Department of Hematology, Ningbo First Hospital, Ningbo 315010, Zhejiang Province, China
Hui-Cong Sun, Adult Internal Medicine, Ningbo Women and Children's Hospital, Ningbo 315012, Zhejiang Province, China
Author contributions: Ouyang GF provided the experimental idea; Wu H and Sun HC collected, sorted, and analyzed the data; Wu H completed the writing of this article; and all authors have read and approved the final draft.
Supported by Zhejiang TCM Science and Technology Project, No. 2023ZL653.
Institutional review board statement: This study was approved by the Institutional Ethics Committee of Ningbo First Hospital.
Informed consent statement: Informed consent was obtained from the patients and their parents/guardians.
Conflict-of-interest statement: We have no financial relationships or any other conflict of interest to disclose.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Gui-Fang Ouyang, MD, Chief Physician, Department of Hematology, Ningbo First Hospital, No. 59 Liuting Street, Ningbo 315010, Zhejiang Province, China. oyguifangoy@163.com
Received: February 27, 2023
Peer-review started: February 27, 2023
First decision: March 10, 2023
Revised: March 24, 2023
Accepted: April 12, 2023
Article in press: April 12, 2023
Published online: May 16, 2023
Processing time: 78 Days and 1.7 Hours
Core Tip

Core Tip: Follicular lymphoma (FL) is a B-cell lymphoma originating from the germinal center and has a low malignancy rate. Completed medical records of 49 patients with follicular lymphoma admitted from June 2010 to June 2021 were retrospectively reviewed. FL was more common in middle-aged and elderly men than in women, mainly involving the lymph nodes and bone marrow. However, an optimal treatment strategy remains unclear. Hemoglobin levels, Ki-67 values, bone marrow involvement, and clinical stage can be used to evaluate prognosis.