Case Report
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Apr 16, 2023; 11(11): 2541-2548
Published online Apr 16, 2023. doi: 10.12998/wjcc.v11.i11.2541
Pregnancy complicated by juxtaglomerular cell tumor of the kidney: A case report
Xian Fu, Gang Deng, Kai Wang, Chang Shao, Li-Ping Xie
Xian Fu, Gang Deng, Kai Wang, Department of Urology, Affiliated Hangzhou First People’s Hospital, Zhejiang University School of Medicine, Hangzhou 310006, Zhejiang Province, China
Chang Shao, Department of Pathology, Affiliated Hangzhou First People’s Hospital, Zhejiang University School of Medicine, Hangzhou 310006, Zhejiang Province, China
Li-Ping Xie, Department of Urology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, Zhejiang Province, China
Author contributions: Fu X, Wang K, and Deng G performed partial nephrectomy; Fu X and Wang K collected the clinical data and compared the current case with the literature; Fu X and Shao C collected the images; Fu X wrote the manuscript; Xie LP critically revised the manuscript; all authors read and approved the final manuscript.
Supported by Medical and Health Technology Project of Hangzhou, No. A20220540.
Informed consent statement: Informed consent was obtained in both written and verbal format from the patient to publish this case report and any accompanying images.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Li-Ping Xie, PhD, Director, Professor, Surgeon, Department of Urology, The First Affiliated Hospital, Zhejiang University School of Medicine, No. 79 Qingchun Road, Shangcheng District, Hangzhou 310003, Zhejiang Province, China. xielp@zju.edu.cn
Received: December 26, 2022
Peer-review started: December 26, 2022
First decision: January 12, 2023
Revised: January 27, 2023
Accepted: March 17, 2023
Article in press: March 17, 2023
Published online: April 16, 2023
Core Tip

Core Tip: Juxtaglomerular cell tumor (JGCT) is a rare endocrine tumor of the kidney. Typical JGCTs are characterized by high serum renin, high aldosterone secretion, severe hypertension, and severe hypokalemia, known as the “three high and one low” phenomenon. The mainstream treatment is surgery. We report an even rarer case of pregnancy complicated with JGCT, who was misdiagnosed with pregnancy-induced hypertension in a primary hospital, and the pregnancy was terminated artificially due to poor response to conservative treatment. The patient was admitted to our hospital for further treatment because her blood pressure remained high after termination of pregnancy and she was diagnosed with JGCT. The patient recovered well after surgery to remove the tumor. In this article, the case is analyzed retrospectively in the context of the literature in an attempt to explore the diagnosis, treatment, and prognosis of this rare disease.