Copyright
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Apr 16, 2023; 11(11): 2405-2411
Published online Apr 16, 2023. doi: 10.12998/wjcc.v11.i11.2405
Published online Apr 16, 2023. doi: 10.12998/wjcc.v11.i11.2405
Advances in translational therapy for locally advanced gastric cancer
Kai Zhao, Ying Na, Hui-Min Xu, Department of General Surgery, Weifang People's Hospital, Weifang 261041, Shandong Province, China
Author contributions: Zhao K, Na Y, and Xu HM designed the study; Zhao K, Na Y, and Xu HM wrote the manuscript; all authors have read and approve the final manuscript.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest or financial interests with any organization involved in the research.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hui-Min Xu, MD, Chief Physician, Department of General Surgery, Weifang People's Hospital, No. 151 Guangwen Street, Kuiwen District, Weifang 261041, Shandong Province, China. xhm001@126.com
Received: January 2, 2023
Peer-review started: January 2, 2023
First decision: January 20, 2023
Revised: February 2, 2023
Accepted: March 17, 2023
Article in press: March 17, 2023
Published online: April 16, 2023
Peer-review started: January 2, 2023
First decision: January 20, 2023
Revised: February 2, 2023
Accepted: March 17, 2023
Article in press: March 17, 2023
Published online: April 16, 2023
Core Tip
Core Tip: In general, for patients with locally advanced gastric cancer, translational therapy can achieve different levels of survival benefit. Immunohistochemistry and genetic testing should be performed before treatment to select a more optimal comprehensive treatment strategy. For patients with locally advanced gastric cancer that is difficult to be resected at the initial stage, translational therapy followed by surgery can improve the survival benefit of patients.