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World J Clin Cases. Apr 16, 2023; 11(11): 2396-2404
Published online Apr 16, 2023. doi: 10.12998/wjcc.v11.i11.2396
Platelet rich fibrin is not a barrier membrane! Or is it?
Amit Arvind Agrawal
Amit Arvind Agrawal, Department of Periodontology and Implantology, Mahatma Gandhi Vidyamandir's Karmaveer Bhausaheb Hiray Dental College and Hospital, Nasik 422003, India
Author contributions: Agrawal AA has solely contributed to the manuscript.
Conflict-of-interest statement: The author declared no conflict of interest related to this manuscript.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Amit Arvind Agrawal, MDS, MPhil, Doctor, Professor, Department of Peridontology and Implantology, Mahatma Gandhi Vidyamandir's Karmaveer Bhausaheb Hiray Dental College and Hospital, Mumbai-Agra Road, Panchavati, Near Kannamwar Bridge, Nasik 422003, India. agrodent@rediffmail.com
Received: January 1, 2023
Peer-review started: January 1, 2023
First decision: January 20, 2023
Revised: January 27, 2023
Accepted: March 17, 2023
Article in press: March 17, 2023
Published online: April 16, 2023
Processing time: 94 Days and 21.5 Hours
Core Tip

Core Tip: Barrier membranes are an important aspect of guided bone and tissue regeneration in periodontics and implant dentistry. Extensive research has been conducted on barrier membranes; however, no single ideal barrier membrane available. Platelet-rich fibrin (PRF) is increasingly becoming popular in dentistry due to its growth factor-secreting properties and is also known to enhance wound healing and soft tissue thickness at the surgical site. However, PRF membranes are labelled as barrier membranes, although they do not fulfil the basic requirements of a barrier membrane.