Clinical Trials Study
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World J Clin Cases. Mar 16, 2022; 10(8): 2420-2428
Published online Mar 16, 2022. doi: 10.12998/wjcc.v10.i8.2420
Identification and predictive analysis for participants at ultra-high risk of psychosis: A comparison of three psychometric diagnostic interviews
Peng Wang, Chuan-Dong Yan, Xiao-Jie Dong, Lei Geng, Chao Xu, Yun Nie, Sheng Zhang
Peng Wang, Chuan-Dong Yan, Xiao-Jie Dong, Lei Geng, Chao Xu, Yun Nie, Sheng Zhang, Department of Psychological Rehabilitation, the Affiliated Wuhan Mental Health Center, Tongji Medical College of Huazhong University of Science & Technology, Wuhan 430022, Hubei Province, China
Author contributions: Wang P designed the research; Dong XJ, Geng L, Nie Y, and Xu C helped to collect the patient’s clinical data; Yan CD and Zhang S analyzed the data; Wang P and Zhang S wrote the paper and revised the manuscript; all authors read and approved the final manuscript.
Supported by the Health Commission of Hubei Province Scientific Research Project, No. WJ2019M016.
Institutional review board statement: The study was approved by the Ethics Committee of Affiliated Wuhan Mental Health Center, Tongji Medical College of Huazhong University of Science & Technology (No. ky2018.45).
Clinical trial registration statement: This study is registered at ClinicalTrials.gov, registration number NCT05042739 (https://clinicaltrials.gov/ct2/show/NCT05042739).
Informed consent statement: Informed written consent was obtained from the patients for publication of this study.
Conflict-of-interest statement: The authors declare having no conflicts of interest.
Data sharing statement: No additional data are available.
CONSORT 2010 statement: The authors have read the CONSORT 2010 Statement, and the manuscript was prepared and revised according to the CONSORT 2010 Statement.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Sheng Zhang, MD, Associate Chief Physician, Department of Psychological Rehabilitation, the Affiliated Wuhan Mental Health Center, Tongji Medical College of Huazhong University of Science & Technology, No. 70 Youyi Road, Qiaokou District, Wuhan 430022, Hubei Province, China. 11024070@qq.com
Received: September 29, 2021
Peer-review started: September 29, 2021
First decision: December 2, 2021
Revised: December 14, 2021
Accepted: January 22, 2022
Article in press: January 22, 2022
Published online: March 16, 2022
Processing time: 162 Days and 20.5 Hours
Core Tip

Core Tip: To address the psychometric comparability of the comprehensive assessment of at risk mental state, Structured Interview for Psychosis-Risk Syndrome and Bonn Scale for the Assessment of Basic Symptoms for the assessment of participants who were lineal relative or collateral relatives by blood up to three generations of patients with schizophrenia, 189 participants were interviewed for an ultra-high risk state. The final conclusion was that there is good diagnostic agreement among these three instruments. Also, these three instruments may assess and detect at-risk mental states in these participants reliably and validly.