Copyright
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Feb 16, 2022; 10(5): 1630-1638
Published online Feb 16, 2022. doi: 10.12998/wjcc.v10.i5.1630
Published online Feb 16, 2022. doi: 10.12998/wjcc.v10.i5.1630
Small-cell carcinoma of the prostate with negative CD56, NSE, Syn, and CgA indicators: A case report
Hong-Jin Shi, Zhi-Nan Fan, Jin-Song Zhang, Bo-Bo Xiong, Hai-Feng Wang, Jian-Song Wang, Department of Urology, The Second Affiliated Hospital, Kunming Medical University, Kunming 650000, Yunnan Province, China
Author contributions: Shi HJ and Fan ZN collected the data, reviewed the literature, and contributed to manuscript drafting; Xiong BB performed the histological analyses and interpretation; Zhang JS and Wang HF was responsible for the revision of the manuscript for important intellectual content; all authors issued final approval for the version to be submitted.
Supported by the National Natural Science Foundation of China , No. 81972395, and No. 82060464.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jin-Song Zhang, Doctor, Doctor, Department of Urology, The Second Affiliated Hospital, Kunming Medical University, No. 374 Dianmian Road, Kunming 650000, Yunnan Province, China. 945933392zjs@sina.com
Received: August 1, 2021
Peer-review started: August 1, 2021
First decision: November 7, 2021
Revised: November 14, 2021
Accepted: December 31, 2021
Article in press: December 31, 2021
Published online: February 16, 2022
Processing time: 193 Days and 21.3 Hours
Peer-review started: August 1, 2021
First decision: November 7, 2021
Revised: November 14, 2021
Accepted: December 31, 2021
Article in press: December 31, 2021
Published online: February 16, 2022
Processing time: 193 Days and 21.3 Hours
Core Tip
Core Tip: Small cell carcinoma of the prostate (SCCP) is a very rare type of prostate tumor, generally characterized by low differentiation, high malignancy, rapid growth, easy diffusion, and poor prognosis. Among SCCP types, mixed SCCP is relatively common, completely simple SCCP is rarely reported, and SCCP with negative neuroendocrine markers is even rarer. This study reports a rare case of SCCP with completely negative neuroendocrine markers, and it found SCCP to be characterized by atypical clinical symptoms, limited treatment options, a short survival period, and a poor prognosis, requiring pathological examination to confirm its diagnosis.