Copyright
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Feb 16, 2022; 10(5): 1536-1547
Published online Feb 16, 2022. doi: 10.12998/wjcc.v10.i5.1536
Published online Feb 16, 2022. doi: 10.12998/wjcc.v10.i5.1536
Castleman disease and TAFRO syndrome: To improve the diagnostic consciousness is the key
Qian-Yun Zhou, Department of Critical Care Medicine, Peking University Shougang Hospital, Beijing 100144, China
Author contributions: Zhou QY designed the research, collected and analyzed data, and wrote the paper.
Supported by the Key Medical Projects of Technical College Development of Shijingshan District.
Institutional review board statement: This study was approved by the Ethics Committee of Peking University Shougang Hospital (approval number: IRBK-2021-010-01).
Informed consent statement: Written informed consent was waived by the Ethics Committee of Peking University Shougang Hospital for retrospective nature of the study.
Conflict-of-interest statement: We have no financial relationships to disclose.
Data sharing statement: The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Qian-Yun Zhou, MD, Doctor, Department of Critical Care Medicine, Peking University Shougang Hospital, No. 9 Jinyuan Zhuang Road, Shijingshan District, Beijing 100144, China. 13521349450@163.com
Received: August 23, 2021
Peer-review started: August 23, 2021
First decision: October 16, 2021
Revised: October 29, 2021
Accepted: January 5, 2022
Article in press: January 5, 2022
Published online: February 16, 2022
Processing time: 171 Days and 22.4 Hours
Peer-review started: August 23, 2021
First decision: October 16, 2021
Revised: October 29, 2021
Accepted: January 5, 2022
Article in press: January 5, 2022
Published online: February 16, 2022
Processing time: 171 Days and 22.4 Hours
Core Tip
Core Tip: This study is a real-world study. Through a retrospective analysis of the diagnosis and treatment process of 39 patients with Castleman disease (CD), we conclude that the clinical classification and pathological classification of CD are not completely independent, and there is an intermediate state or transition state between the two extreme manifestations. TAFRO syndrome is still classified as a special subtype of idiopathic multicentric Castleman disease (iMCD). TAFRO syndrome is easier to identify than iMCD-not otherwise specified because of its unique pathological and clinical features.