Clinical and Translational Research
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Feb 16, 2022; 10(5): 1485-1497
Published online Feb 16, 2022. doi: 10.12998/wjcc.v10.i5.1485
Effect of prior malignancy on the prognosis of gastric cancer and somatic mutation
Xin Yin, Xing-Kang He, Ling-Yun Wu, Sen-Xiang Yan
Xin Yin, Ling-Yun Wu, Sen-Xiang Yan, Department of Radiation Oncology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310000, Zhejiang Province, China
Xing-Kang He, Department of Gastroenterology, Sir Run Run Shaw Hospital, Hangzhou 310000, Zhejiang Province, China
Author contributions: Yin X, Yan SX, and He XK conceived and designed the study, conducted data extraction statistical analyses, interpreted the study results, and wrote the first draft of the manuscript; Wu LY extracted and analyzed the data, and interpreted the study results; All authors edited and critically revised the final version of the manuscript.
Institutional review board statement: The data that support the findings of this study are publicly available. The current study does not require approval from an ethics committee.
Conflict-of-interest statement: The authors declare that they have no competing interests.
Data sharing statement: The data that support the findings of this study are publicly available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Sen-Xiang Yan, MD, Chief Doctor, Department of Radiation Oncology, the First Affiliated Hospital, College of Medicine, Zhejiang University, the First Affiliated Hospital, College of Medicine, Zhejiang University, 79 Qingchun Road, Hangzhou, Zhejiang 310003, PR China, Hangzhou 310000, Zhejiang Province, China. yansenxiang@zju.edu.cn
Received: July 10, 2021
Peer-review started: July 10, 2021
First decision: November 8, 2021
Revised: November 8, 2021
Accepted: January 6, 2022
Article in press: January 6, 2022
Published online: February 16, 2022
Processing time: 215 Days and 13.3 Hours
Core Tip

Core Tip: We identified eligible cases during 2004-2011 from the Surveillance, Epidemiology, and End Results database and compared the clinical features of gastric cancer (GC) patients with/without prior cancer. We found that patients with a history of prior cancer tended to be elderly, with a more localized stage and less positive lymph nodes. The prognosis of GC patients with diagnosis of prior cancer was not inferior to primary GC.