Case Report
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Nov 26, 2022; 10(33): 12447-12454
Published online Nov 26, 2022. doi: 10.12998/wjcc.v10.i33.12447
Synchronous early gastric and intestinal mucosa-associated lymphoid tissue lymphoma in a Helicobacter pylori-negative patient: A case report
Sheng-Nian Lu, Cheng Huang, Ling-Li Li, Lian-Jun Di, Jin Yao, Bi-Guang Tuo, Rui Xie
Sheng-Nian Lu, Cheng Huang, Ling-Li Li, Lian-Jun Di, Bi-Guang Tuo, Rui Xie, Department of Gastroenterology, Digestive Disease Hospital, Affiliated Hospital of Zunyi Medical University, Zunyi 563003, Guizhou Province, China
Jin Yao, Pathology Department, Affiliated Hospital of Zunyi Medical University, Zunyi 563003, Guizhou Province, China
Author contributions: Lu SN wrote the manuscript; Huang C, Di LJ and Li LL diagnosed the patient and contributed to the endoscopic; Yao J contributed to pathological diagnosis and provided the pathological images; Tuo BG and Xie R performed the treatment and revised the manuscript; and all authors have read and approve the final manuscript.
Supported by Master' s Start-up Fund of the Affiliated Hospital of Zunyi Medical College, No. [2015]34; Basic Research Projects of Science and Technology Department of Guizhou Province, No. Qian Ke He-zk[2022]-646; and Collaborative Innovation Center of Chinese Ministry of Education, No. 2020-39.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Rui Xie, PhD, Full Professor, Department of Gastroenterology, Digestive Disease Hospital, Affiliated Hospital of Zunyi Medical University, No. 149 Dalian Road, Zunyi 563003, Guizhou Province, China. xr19841029@aliyun.com
Received: September 16, 2022
Peer-review started: September 16, 2022
First decision: September 27, 2022
Revised: October 3, 2022
Accepted: October 31, 2022
Article in press: October 31, 2022
Published online: November 26, 2022
Processing time: 68 Days and 0.1 Hours
Core Tip

Core Tip: Mucosa-associated lymphoid tissue (MALT) lymphoma is a subtype of non-Hodgkin’s lymphoma that is rarely found in both the stomach and colon. Diagnosis of MALT lymphoma is challenging because of nonspecific symptoms and diverse presentations of endoscopic findings. Helicobacter pylori (H. pylori) infection is the initial event in gastric MALT lymphoma. We report a case of H. pylori-negative gastric MALT lymphoma mimicking a gastric stromal tumor, together with a rectal presentation of intestinal MALT with a polyp-like appearance, which were treated endoscopically with complete remission.