Case Report
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Oct 26, 2022; 10(30): 11031-11036
Published online Oct 26, 2022. doi: 10.12998/wjcc.v10.i30.11031
Neonatal Cri du chat syndrome with atypical facial appearance: A case report
Meng-Meng Bai, Wen Li, Lin Meng, Yan-Feng Sang, Yu-Jie Cui, Hui-Ying Feng, Zhi-Tao Zong, Hong-Bo Zhang
Meng-Meng Bai, Department of Pediatrics, Maternal and Child Health Hospital of Hubei Province, Wuhan 430070, Hubei Province, China
Wen Li, Lin Meng, Yan-Feng Sang, Yu-Jie Cui, Hui-Ying Feng, Department of Pediatrics, Chengde Central Hospital, Chengde Medical University, Chengde 067000, Hebei Province, China
Zhi-Tao Zong, Department of Neurosurgery, Jiujiang Hospital of Traditional Chinese Medicine, Jiujiang 332005, Jiangxi Province, China
Hong-Bo Zhang, Department of Neurosurgery, The Second Affiliated Hospital of Nanchang University, Nanchang 330006, Jiangxi Province, China
Author contributions: Bai MM and Meng L carried out the data collection and drafted the manuscript; Sang YF, Cui YJ and Feng HY carried out the editing of the manuscript and contributed to review of the data; Li W, Zong ZT and Zhang HB conceived the study, participated in its design, coordinated and frequently edited the manuscript; All authors read and approved the final manuscript.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Wen Li, MD, PhD, Professor, Department of Pediatrics, Chengde Central Hospital, Chengde Medical University, No. 66 Guangren Avenue, Shuangqiao District, Chengde 067000, Hebei Province, China. wenwen9155@sina.com
Received: April 24, 2022
Peer-review started: April 24, 2022
First decision: June 8, 2022
Revised: July 4, 2022
Accepted: September 23, 2022
Article in press: September 23, 2022
Published online: October 26, 2022
Processing time: 179 Days and 15 Hours
Core Tip

Core Tip: A 2-d-old male child presented to our hospital with poor postnatal reaction and poor milk intake. The baby's crying and sucking is weak, reaction and feeding time is poor and the baby has nausea and vomiting. Karyotype analysis showed that the chromosomes were 46, XY, deletion (5) p15. Whole genome microarray analysis (named ISCN2013) showed that the chromosomes of the child were male karyotypes and contained three chromosomal abnormalities. Among them, loss of 5p15.2pter (113576-13464559) was associated with cat call syndrome. After a 3 mo of follow-up, the child still vomited repeatedly, had poor milk intake, did not return to normal growth, had developmental retardation and had a poor directional response.