Copyright
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Oct 26, 2022; 10(30): 10906-10920
Published online Oct 26, 2022. doi: 10.12998/wjcc.v10.i30.10906
Published online Oct 26, 2022. doi: 10.12998/wjcc.v10.i30.10906
Prognostic impact of number of examined lymph nodes on survival of patients with appendiceal neuroendocrine tumors
Rui Du, Jiang-Wei Xiao, Department of Gastrointestinal Surgery, The First Affiliated Hospital of Chengdu Medical College, Chengdu 610500, Sichuan Province, China
Author contributions: Xiao JW conceived the study; Du R collected, performed, and analyzed the data, and wrote the paper; Xiao JW and Du R carried out the data statistical processing and revised the paper; and All authors reviewed the results and approved the final version of the manuscript.
Institutional review board statement: The study was approved by the ethics committee of the First Affiliated Hospital of Chengdu Medical College.
Informed consent statement: The requirement for informed consent was waived by the committee because of the retrospective nature of the study.
Conflict-of-interest statement: All authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jiang-Wei Xiao, MD, PhD, Professor, Department of Gastrointestinal Surgery, The First Affiliated Hospital of Chengdu Medical College, No. 278 Baoguang Avenue, Xindu District, Chengdu 610500, Sichuan Province, China. xiaojiangwei2018@163.com
Received: March 19, 2022
Peer-review started: March 19, 2022
First decision: May 1, 2022
Revised: May 8, 2022
Accepted: August 1, 2022
Article in press: August 1, 2022
Published online: October 26, 2022
Peer-review started: March 19, 2022
First decision: May 1, 2022
Revised: May 8, 2022
Accepted: August 1, 2022
Article in press: August 1, 2022
Published online: October 26, 2022
Core Tip
Core Tip: This study aimed to explore factors that have an influence on survival of patients with appendiceal neuroendocrine tumors. We identified the optimal number of examined lymph nodes that could achieve the best survival for patients with appendiceal neuroendocrine tumors with different lymph node statuses. Furthermore, lymph node ratio takes both examined lymph nodes and positive lymph nodes into account. We also identified the optimal value of lymph node ratio that could achieve the best survival for node-positive patients.