Clinical Trials Study
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jan 21, 2022; 10(3): 870-881
Published online Jan 21, 2022. doi: 10.12998/wjcc.v10.i3.870
Role of carbon nanotracers in lymph node dissection of advanced gastric cancer and the selection of preoperative labeling time
Kai Zhao, Bao-Qiang Shan, Yan-Peng Gao, Jia-You Xu
Kai Zhao, Bao-Qiang Shan, Yan-Peng Gao, Jia-You Xu, Department of General Surgery, WFPH, Weifang 261400, Shandong Province, China
Author contributions: Zhao K, Shan BQ and Gao YP designed the research study; Zhao K, Shan BQ performed the research; Zhao K, Shan BQ, Gao YP contributed new reagents and analytic tools; Zhao K, Shan BQ and Xu JY analyzed the data and wrote the manuscript; all authors have read and approve the final manuscript.
Institutional review board statement: The study was reviewed and approved by the Weifang People’s Hospital Institutional Review Board (Approval No. 2021-021).
Clinical trial registration statement: This study is registered at chinese clinical trial registry: https://www.chictr.org.cn, registration No. ChiCTR2100050003.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All authors of this manuscript have directly participated in planning, execution, and analysis of this study. The contents of this manuscript have not been copyrighted or published previously. The contents of this manuscript are not now under consideration for publication elsewhere. There are no directly related manuscripts or abstracts, published or unpublished, by any authors of this manuscript. No financial support or incentive has been provided for this manuscript.
Data sharing statement: This study had already registered at Resman (http://www.medresman.org.cn) and its data is available from http://www.medresman.org.cn/uc/project/projectedit.aspx?proj=8208, also available from the corresponding author: xujiayou5252@sina.com
CONSORT 2010 statement: The authors have read the CONSORT 2010 statement, and the manuscript was prepared and revised according to the CONSORT 2010 statement.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jia-You Xu, MD, Chief Doctor, General Surgery, WFPH, No. 152 Guangwen Street, Weifang 261400, Shandong Province, China. xujiayou5252@sina.com
Received: August 18, 2021
Peer-review started: August 18, 2021
First decision: October 3, 2021
Revised: October 19, 2021
Accepted: December 22, 2021
Article in press: December 22, 2021
Published online: January 21, 2022
Processing time: 150 Days and 11.2 Hours
Core Tip

Core Tip: This study investigated the role of carbon nanoparticles in lymph node dissection during gastrectomy, and discussed the relationship between the timing for preoperative labeling and the number of lymph nodes dissected. It was found that carbon nanoparticle labeling has a role in guiding laparoscopic lymph node dissection of gastric cancer. Preoperative submucosal injection of carbon nanoparticles could significantly improve the detection rate of lymph nodes, which is conducive to pathological staging and subsequent comprehensive antitumor therapy.