Link between COVID-19 vaccines and myocardial infarction

doi:10.12998/wjcc.v10.i28.10109

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World Journal of Clinical Cases

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Cases. Oct 6, 2022; 10(28): 10109-10119
Published online Oct 6, 2022. doi: 10.12998/wjcc.v10.i28.10109

Link between COVID-19 vaccines and myocardial infarction

Umema Zafar, Hamna Zafar, Mian Saad Ahmed, Madiha Khattak

Umema Zafar, Madiha Khattak, Department of Physiology, Khyber Medical College, Peshawar 25000, Pakistan

Hamna Zafar, Department of Medicine, Khyber Teaching Hospital, Peshawar 25000, Pakistan

Mian Saad Ahmed, Department of Forensic Medicine, Khyber Medical College, Peshawar 25000, Pakistan

Author contributions: Zafar U and Zafar H designed the research and analyzed the data and checked paper for final review; Ahmed MS and Khattak M performed the research and wrote the paper.

Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.

PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised in accordance with this checklist.

Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Umema Zafar, MBBS, MPhil, Assistant Professor, Doctor, Department of Physiology, Khyber Medical College, Peshawar University Campus, Peshawar 25000, Pakistan. umema.com@gmail.com

Received: May 30, 2022
Peer-review started: May 30, 2022
First decision: July 14, 2022
Revised: July 20, 2022
Accepted: September 1, 2022
Article in press: September 1, 2022
Published online: October 6, 2022
Processing time: 119 Days and 23.9 Hours

Core Tip

Core Tip: Mechanisms like vaccine-induced thrombotic thrombocytopenia and myocarditis complication have been identified in the literature linking myocardial infarction with coronavirus disease 2019 (COVID-19) vaccination. The majority of myocardial infarction cases reported were after vaccination with the vaccine from AstraZeneca, were ST-segment elevation, and were reported after first dose of vaccine. Although there are reports of myocardial infarction after COVID-19 vaccination, no definitive link was found in the previous literature linking the two.