Case Report
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Sep 26, 2022; 10(27): 9768-9775
Published online Sep 26, 2022. doi: 10.12998/wjcc.v10.i27.9768
Histiocytoid giant cellulitis-like Sweet syndrome at the site of sternal aspiration: A case report and review of literature
De-Wan Zhao, Jing Ni, Xiu-Li Sun
De-Wan Zhao, Xiu-Li Sun, Department of Hematology, The First Affiliated Hospital of Dalian Medical University, Dalian 116014, Liaoning Province, China
Jing Ni, Department of Dermatology, The First Affiliated Hospital of Dalian Medical University, Dalian 116011, Liaoning Province, China
Author contributions: Zhao DW and Sun XL examined and treated the patient; Ni J was responsible for the pathological diagnosis; Zhao DW wrote the manuscript and generated all the figures; Sun XL supervised the manuscript preparation; and all authors issued final approval for the version to be submitted.
Supported by the National Natural Science Foundation of China, No. 82100125.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Corresponding author: Xiu-Li Sun, MD, PhD, Chief Doctor, Professor, Department of Hematology, The First Affiliated Hospital of Dalian Medical University, No. 193 Lianhe Road, Shahekou District, Dalian 116014, Liaoning Province, China.
Received: January 11, 2022
Peer-review started: January 11, 2022
First decision: March 15, 2022
Revised: March 26, 2022
Accepted: August 14, 2022
Article in press: August 14, 2022
Published online: September 26, 2022
Core Tip

Core Tip: We describe the case of a 52-year-old male with myelodysplastic syndrome who developed histiocytoid giant cellulitis-like Sweet syndrome (SS) at a sternal puncture site. The patient had unique clinical presentations that have never been reported before, and the disease profile was difficult to distinguish from cellulitis. Cellulitis that has failed to respond to broad-spectrum anti-microbial therapy requires a skin biopsy. For patients with concurrent myeloid neoplasm and SS, intensive treatment is necessary since SS and myeloid leukemia cutis may be different stages of the same disease and both indicate a poor prognosis.