Opinion Review
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Sep 26, 2022; 10(27): 9550-9555
Published online Sep 26, 2022. doi: 10.12998/wjcc.v10.i27.9550
Psychiatric disorders and pain: The recurrence of a comorbidity
Gentian Vyshka
Gentian Vyshka, Department of Biomedical and Experimental, Faculty of Medicine, University of Medicine, Tirana 1005, Albania
Author contributions: Vyshka G has conceived and written the manuscript; revised it in the present version, and collected the references.
Conflict-of-interest statement: All authors declare no conflict of interests.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Gentian Vyshka, MD, Professor, Department of Biomedical and Experimental, Faculty of Medicine, University of Medicine, Rr. Dibres 371, Tirana 1005, Albania. gvyshka@gmail.com
Received: May 8, 2022
Peer-review started: May 8, 2022
First decision: June 2, 2022
Revised: June 12, 2022
Accepted: August 16, 2022
Article in press: August 16, 2022
Published online: September 26, 2022
Core Tip

Core Tip: Chronic pain and psychiatric disorders concur often and the prevalence of this comorbidity outnumbers the odds of a mere coincidence. Identifying the first causative factor will be difficult, especially when the situation is complex and therapies have given poor results, if not failed completely. The debatable question of which comes first: The psychiatric disorder or the painful injury, nevertheless can be simplified within the model of a central sensitization, seemingly upheld from the model of PTSD and similar medical occurrences. Thus, an initial injury of psychological nature could lower pain perception threshold, and lead subsequently to chronic pain disorders.