Case Report
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Aug 26, 2022; 10(24): 8728-8734
Published online Aug 26, 2022. doi: 10.12998/wjcc.v10.i24.8728
Spontaneous acute epidural hematoma secondary to skull and dural metastasis of hepatocellular carcinoma: A case report
Guang-Zhao Lv, Guo-Chao Li, Wei-Tai Tang, Dong Zhou, Yong Yang
Guang-Zhao Lv, Dong Zhou, Yong Yang, Department of Neurosurgery, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, Guangdong Province, China
Guo-Chao Li, Wei-Tai Tang, Department of Neurosurgery, Luoding People’s Hospital, Yunfu 527200, Guangdong Province, China
Author contributions: Lv GZ, Li GC and Yang Y were the patient’s neurosurgeons, reviewed the literature and contributed to manuscript drafting; Lv GZ reviewed the literature and contributed to manuscript drafting; Tang WT analyzed and interpreted the imaging findings; Zhou D was responsible for the revision of the manuscript for important intellectual content; all authors issued final approval for the version to be submitted.
Supported by Natural Science Foundation of China, No. 81901250; Natural Science Foundation of Guangdong Province, No. 2019A1515010104 and No. 2022A1515012540; High-level Hospital Construction Project of Guangdong Provincial People’s Hospital, No. DFJH201924; and Science and Technology Program of Guangzhou, No. 202002030128.
Informed consent statement: The patient's legal guardian provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: We have confirmed all the items on the CARE checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yong Yang, MD, PhD, Neurosurgeon, Department of Neurosurgery, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, No. 106 Zhongshan Er Road, Yuexiu District, Guangzhou 510080, Guangdong Province, China. yangyong@gdph.org.cn
Received: March 17, 2022
Peer-review started: March 17, 2022
First decision: May 30, 2022
Revised: June 12, 2022
Accepted: July 18, 2022
Article in press: July 18, 2022
Published online: August 26, 2022
Processing time: 151 Days and 9.7 Hours
Core Tip

Core Tip: We present a case of hepatocellular carcinoma (HCC) metastasis to the skull and dura mater with spontaneous acute epidural hematoma (AEDH). This is the first report of spontaneous AEDH secondary to skull and dura mater metastasis from HCC in the Chinese population. Pathological examination provided evidence that the dura mater was one of the targets for HCC metastasis and could also lead to AEDH in addition to the reported skull metastases. We summarize the characteristics of the 8 reported cases worldwide, discuss the possible cause of AEDH, and offer advice for clinical practice.