Randomized Controlled Trial
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Aug 26, 2022; 10(24): 8615-8624
Published online Aug 26, 2022. doi: 10.12998/wjcc.v10.i24.8615
High-flow nasal cannula oxygen therapy during anesthesia recovery for older orthopedic surgery patients: A prospective randomized controlled trial
Xiao-Na Li, Cheng-Cheng Zhou, Zi-Qiang Lin, Bin Jia, Xiang-Yu Li, Gao-Feng Zhao, Fei Ye
Xiao-Na Li, Cheng-Cheng Zhou, Zi-Qiang Lin, Second Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou 510000, Guangdong Province, China
Bin Jia, Xiang-Yu Li, Gao-Feng Zhao, Fei Ye, Department of Anaesthesiology, Guangdong Provincial Hospital of Chinese Medicine (The Second Affiliated Hospital of Guangzhou University of Chinese Medicine), Guangzhou 510000, Guangdong Province, China
Author contributions: Li XN was the main contributor to this work; Li XN, Zhou CC, Jia B, Li XY, Zhao GF, and Ye F designed the research; Li XN and Ye F performed the research; Lin ZQ, Li XY contributed the new analytic tools; Li XN and Zhou CC analyzed the data; Li XN and Ye F wrote the paper.
Institutional review board statement: The study was reviewed and approved by the Institutional Ethics Committee of the Ethics Committee of Guangdong Hospital of Conventional Chinese Medicine on January 29, 2021, No. YF2021-014-01.
Clinical trial registration statement: This study is registered at Clinical hospital center“Chinese Clinical Trial Registry”trial registry, No. ChiCTR2100044463.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: There are no conflicts of interest to report.
Data sharing statement: Technical appendix, statistical code, and dataset available from the corresponding author at yepainclinic@163.com.
CONSORT 2010 statement: The authors have read the CONSORT 2010 statement, and the manuscript was prepared and revised according to the CONSORT 2010 statement.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Fei Ye, PhD, Doctor, Department of Anaesthesiology, Guangdong Provincial Hospital of Chinese Medicine (The Second Affiliated Hospital of Guangzhou University of Chinese Medicine), No. 111 Dade Road, Guangzhou 510000, Guangdong Province, China. yepainclinic@163.com
Received: April 11, 2022
Peer-review started: April 11, 2022
First decision: May 30, 2022
Revised: June 11, 2022
Accepted: July 25, 2022
Article in press: July 25, 2022
Published online: August 26, 2022
Processing time: 126 Days and 17.7 Hours
Core Tip

Core Tip: This prospective randomized controlled study involving 60 patients evaluated the effects of different oxygen delivery methods. Additionally, the study investigated the clinical efficacy of high-flow nasal cannula oxygen (HFNCO) on the recovery period of older orthopedic patients. The current results showed that HFNCO can improve oxygen partial pressure and respiratory function in older patients undergoing orthopedic surgery with general anesthesia under endotracheal intubation.