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World J Clin Cases. Aug 6, 2022; 10(22): 7653-7664
Published online Aug 6, 2022. doi: 10.12998/wjcc.v10.i22.7653
Update on gut microbiota in gastrointestinal diseases
Atsushi Nishida, Kyohei Nishino, Masashi Ohno, Keitaro Sakai, Yuji Owaki, Yoshika Noda, Hirotsugu Imaeda
Atsushi Nishida, Kyohei Nishino, Masashi Ohno, Keitaro Sakai, Yuji Owaki, Yoshika Noda, Hirotsugu Imaeda, Department of Gastroenterology and Hepatology, Nagahama City Hospital, Nagahama 526-8580, Japan
Author contributions: Nishida A wrote the paper; Nishino K, Masashi O, Sakai K, Owaki Y, Noda Y, and Imaeda H contributed critical revision of the manuscript.
Conflict-of-interest statement: No conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Atsushi Nishida, MD, PhD, Chief Doctor, Department of Gastroenterology and Hepatology, Nagahama City Hospital, 313 Oinuicho, Nagahama 526-8580, Japan. atsuda@belle.shiga-med.ac.jp
Received: February 8, 2022
Peer-review started: February 8, 2022
First decision: April 5, 2022
Revised: April 20, 2022
Accepted: June 22, 2022
Article in press: June 22, 2022
Published online: August 6, 2022
Processing time: 163 Days and 8.3 Hours
Core Tip

Core Tip: In this review, we discuss the gut microbiota in human gastrointestinal diseases, including Clostridioides difficile infection, inflammatory bowel disease, and irritable bowel syndrome. We review the role of the gut microbiota in human gastrointestinal diseases and the therapeutic options for manipulating it.