Retrospective Study
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jul 26, 2022; 10(21): 7293-7301
Published online Jul 26, 2022. doi: 10.12998/wjcc.v10.i21.7293
Preoperative neoadjuvant chemotherapy in patients with breast cancer evaluated using strain ultrasonic elastography
Hong-Yu Pan, Qian Zhang, Wen-Jing Wu, Xia Li
Hong-Yu Pan, Qian Zhang, Wen-Jing Wu, Xia Li, Department of Ultrasound, Wuhan Fourth Hospital; Puai Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, Hubei Province, China
Author contributions: Pan HY and Li X designed this study; Pan HY wrote the manuscript; Pan HY, Zhang Q, Wu WJ and Li X collected the data; and all authors have read and approve the final manuscript.
Institutional review board statement: This study was reviewed and approved by the Fourth Hospital Puai Hospital, Tongji Medical College, Huazhong University of Science and Technology.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All the authors declare no conflict of interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xia Li, MD, Technician, Department of Ultrasound, Wuhan Fourth Hospital; Puai Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 66 Xuefu South Road, Wuhan 430000, Hubei Province, China. lixia2021314@163.com
Received: March 15, 2022
Peer-review started: March 15, 2022
First decision: April 13, 2022
Revised: April 25, 2022
Accepted: June 24, 2022
Article in press: June 24, 2022
Published online: July 26, 2022
Processing time: 117 Days and 23.1 Hours
Core Tip

Core Tip: The changes in a malignant tumor should be evaluated to determine the effects of preoperative neoadjuvant chemotherapy in breast cancer. However, conventional ultrasonography is not as sensitive as the current pathological reactivity detection method and may not meet clinical needs in determining the effect of neoadjuvant chemotherapy. A relatively novel method called strain ultrasound elastography was used in 90 patients with breast cancer in this study. It was found to be more effective and sensitive in the evaluation of the effects of neoadjuvant chemotherapy in patients with breast cancer.