Pan HY, Zhang Q, Wu WJ, Li X. Preoperative neoadjuvant chemotherapy in patients with breast cancer evaluated using strain ultrasonic elastography. World J Clin Cases 2022; 10(21): 7293-7301 [PMID: 36158032 DOI: 10.12998/wjcc.v10.i21.7293]
Corresponding Author of This Article
Xia Li, MD, Technician, Department of Ultrasound, Wuhan Fourth Hospital; Puai Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 66 Xuefu South Road, Wuhan 430000, Hubei Province, China. lixia2021314@163.com
Research Domain of This Article
Radiology, Nuclear Medicine & Medical Imaging
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Jul 26, 2022; 10(21): 7293-7301 Published online Jul 26, 2022. doi: 10.12998/wjcc.v10.i21.7293
Preoperative neoadjuvant chemotherapy in patients with breast cancer evaluated using strain ultrasonic elastography
Hong-Yu Pan, Qian Zhang, Wen-Jing Wu, Xia Li
Hong-Yu Pan, Qian Zhang, Wen-Jing Wu, Xia Li, Department of Ultrasound, Wuhan Fourth Hospital; Puai Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, Hubei Province, China
Author contributions: Pan HY and Li X designed this study; Pan HY wrote the manuscript; Pan HY, Zhang Q, Wu WJ and Li X collected the data; and all authors have read and approve the final manuscript.
Institutional review board statement: This study was reviewed and approved by the Fourth Hospital Puai Hospital, Tongji Medical College, Huazhong University of Science and Technology.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All the authors declare no conflict of interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xia Li, MD, Technician, Department of Ultrasound, Wuhan Fourth Hospital; Puai Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 66 Xuefu South Road, Wuhan 430000, Hubei Province, China. lixia2021314@163.com
Received: March 15, 2022 Peer-review started: March 15, 2022 First decision: April 13, 2022 Revised: April 25, 2022 Accepted: June 24, 2022 Article in press: June 24, 2022 Published online: July 26, 2022 Processing time: 117 Days and 23.1 Hours
ARTICLE HIGHLIGHTS
Research background
Breast cancer has the seventh highest mortality rate of all cancers in China and has the fifth highest cancer mortality in women, accounting for 8.2% of all female malignant tumors and seriously impacting women’s health and quality of life.
Research motivation
Early detection, diagnosis, and treatment are key to reducing mortality and improving cure rates.
Research objectives
Strain ultrasound elastography (SUE) is a new type of ultrasound technology that can determine relative tissue hardness by evaluating the desmoplastic changes in a tissue to differentiate between benign and malignant tumors.
Research methods
It is a way to diagnose tumors and diffuse diseases that cannot be detected by conventional ultrasound.
Research results
Of the patients analyzed, 20 had a pathological complete remission (pCR) while 70 did not achieve pCR after neoadjuvant chemotherapy (NAC).
Research conclusions
Strain ultrasonic elastography may be used to evaluate the effects of preoperative NAC in patients with breast cancer.
Research perspectives
SUE is a new type of ultrasound technology that can determine relative tissue hardness by evaluating the desmoplastic changes in a tissue to differentiate between benign and malignant tumors.
