Case Report
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jun 6, 2022; 10(16): 5502-5509
Published online Jun 6, 2022. doi: 10.12998/wjcc.v10.i16.5502
Mixed large and small cell neuroendocrine carcinoma of the stomach: A case report and review of literature
Ze-Feng Li, Hai-Zhen Lu, Ying-Tai Chen, Xiao-Feng Bai, Tong-Bo Wang, He Fei, Dong-Bing Zhao
Ze-Feng Li, Ying-Tai Chen, Xiao-Feng Bai, Tong-Bo Wang, He Fei, Dong-Bing Zhao, Department of Pancreatic and Gastric Surgical Oncology, National Cancer Center/National Clinical Research for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
Hai-Zhen Lu, Department of Pathology, National Cancer Center/National Clinical Research for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
Author contributions: Li ZF and Lu HZ contributed equally to this work; Zhao DB contributed to the conception and design of the study; Li ZF collected the data and wrote the initial draft of the manuscript; Lu HZ reviewed the pathological sections and analyzed and interpreted the data; Chen YT and Bai XF contributed to drafting and revising the manuscript; Wang TB and Fei H participated in the clinical management and follow-up of the patient; all authors made substantial contributions to the intellectual content of this paper and approved the submitted version.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest related to this manuscript.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Dong-Bing Zhao, MD, Professor, Department of Pancreatic and Gastric Surgical Oncology, National Cancer Center/National Clinical Research for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 17 Panjiayuan Nanli, Beijing 100021, China. dbzhao@cicams.ac.cn
Received: December 27, 2021
Peer-review started: December 27, 2021
First decision: February 8, 2022
Revised: February 18, 2022
Accepted: April 3, 2022
Article in press: April 3, 2022
Published online: June 6, 2022
Processing time: 157 Days and 8.2 Hours
Core Tip

Core Tip: To the best of our knowledge, there have been no previous reports on mixed large and small cell neuroendocrine carcinoma of the stomach. This case might contribute to improving our understanding of gastric neuroendocrine carcinoma. More basic and clinical researches are warranted to clarify the heterogeneity of gastric neuroendocrine carcinoma.