Case Report
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jun 6, 2022; 10(16): 5406-5413
Published online Jun 6, 2022. doi: 10.12998/wjcc.v10.i16.5406
Glomangiomatosis - immunohistochemical study: A case report
Ruo-Chen Wu, Ying-Hua Gao, Wen-Wen Sun, Xiang-Yun Zhang, Shu-Peng Zhang
Ruo-Chen Wu, Ying-Hua Gao, Wen-Wen Sun, Shu-Peng Zhang, Department of Pathology, The Second Affiliated Hospital of Shandong First Medical University, Taian 271000, Shandong Province, China
Xiang-Yun Zhang, Department of Pathology, The First People’s Hospital of Jining City, Jining 272000, Shandong Province, China
Author contributions: Zhang SP was the patient’s doctor in charge, was responsible for collecting the medical history, and contributed to the revision of the manuscript; Wu RC was responsible for collecting the medical history, reviewing the literature, drafting the paper, and contributing to the revising of the manuscript; Gao YH, Zhang XY, and Sun WW revised the manuscript; All authors issued final approval for the submitted version.
Supported by Academic Promotion Program of Shandong First Medical University, No. 2019QL017.
Informed consent statement: Written informed consent was obtained from the patient for publication of this report.
Conflict-of-interest statement: The authors declare that there is no conflict of interest
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Shu-Peng Zhang, MD, Doctor, Department of Pathology, The Second Affiliated Hospital of Shandong First Medical University, No. 706 Taishan Street, Taishan District, Taian 271000, Shandong Province, China. zhangshp01@163.com
Received: September 16, 2021
Peer-review started: September 16, 2021
First decision: December 17, 2021
Revised: February 9, 2022
Accepted: April 2, 2022
Article in press: April 2, 2022
Published online: June 6, 2022
Processing time: 258 Days and 21.4 Hours
Core Tip

Core Tip: We describe a case of glomangiomatosis with many nodular masses in the soft tissues of the right foot and calf, presented by a 55-year-old woman. Pigmented villous nodular synovitis was observed via imaging. Microscopically, nested vascular globular cells around the blood vessel wall were observed. After resection, there was no recurrence during the 1-year follow-up. Although growth may be diffuse or infiltrating and invasive, glomangiomatosis does not meet the identifying standards for malignant glomus tumors.