Case Report
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. May 26, 2022; 10(15): 4917-4922
Published online May 26, 2022. doi: 10.12998/wjcc.v10.i15.4917
Paradoxical herniation after decompressive craniectomy provoked by mannitol: A case report
Chuan Du, Hua-Juan Tang, Shuang-Ming Fan
Chuan Du, Shuang-Ming Fan, Neurosurgery, the Affiliated Hospital of Chengdu University, Chengdu 610000, Sichuan Province, China
Hua-Juan Tang, Neurology, West China Hospital, Sichuan University, Chengdu 610000, Sichuan Province, China
Author contributions: Du C and Tang HJ designed this work, analyzed the data, and wrote the manuscript; Du C collected the patient's clinical data; Fan SM and Du C performed the surgery; Fan SM designed and reviewed this paper; all authors have read and approved the final version of this manuscript.
Supported by the Natural Science Project of Chengdu University Clinical School, No. 2020YYZ18.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Shuang-Ming Fan, MD, Attending Doctor, Neurosurgery, The Affiliated Hospital of Chengdu University, No. 82, North Section 2, Second Ring Road, Chengdu 610000, Sichuan Province, China. 297551802@qq.com
Received: September 19, 2021
Peer-review started: September 19, 2021
First decision: December 10, 2021
Revised: December 20, 2021
Accepted: April 3, 2022
Article in press: April 3, 2022
Published online: May 26, 2022
Processing time: 246 Days and 21.8 Hours
Core Tip

Core Tip: The paradoxical herniation is a rare but life-threatening complication in patients with large decompressive craniectomies. This case report suggests that mannitol treatment after a large decompressive craniectomy can cause a paradoxical herniation. Early recognition and proper treatment can save a patient's life.