Case Report
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. May 16, 2022; 10(14): 4654-4660
Published online May 16, 2022. doi: 10.12998/wjcc.v10.i14.4654
Management about intravesical histological transformation of prostatic mucinous carcinoma after radical prostatectomy: A case report
Sheng-Jiang Bai, Li Ma, Min Luo, Hang Xu, Lu Yang
Sheng-Jiang Bai, Li Ma, Min Luo, Hang Xu, Lu Yang, Department of Urology, Institute of Urology, West China Hospital of Sichuan University, Chengdu 610041, Sichuan Province, China
Author contributions: Bai SJ reviewed all the literature available about prostate mucinous carcinoma and mucinous carcinoma with signet ring cells up until June 2021 and was a major contributor to the manuscript; Ma L performed the literature review and made critical revisions of the manuscript; Luo M and Xu H performed the data acquisition and contributed to partial writing of the manuscript; Yang L guided throughout the writing process as well as funded the project; All authors read and approved the final manuscript.
Supported by Science and Technology Department of Sichuan Province, No. 21GJHZ0246.
Informed consent statement: Written informed consent for publication of the patient’s clinical details and clinical images was obtained from the patient.
Conflict-of-interest statement: The authors declare no potential conflicts of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Lu Yang, PhD, Assistant Professor, Chief Doctor, Department of Urology, Institute of Urology, West China Hospital of Sichuan University, No. 37 Guoxue Alley, Wuhou District, Chengdu 610041, Sichuan Province, China. wycleflue@163.com
Received: November 24, 2021
Peer-review started: November 24, 2021
First decision: January 22, 2022
Revised: February 5, 2022
Accepted: March 16, 2022
Article in press: March 16, 2022
Published online: May 16, 2022
Processing time: 170 Days and 5.9 Hours
Core Tip

Core Tip: Prostatic mucinous carcinoma with signet ring cells (MCSRC) is a very rare morphologic variant of prostate cancer. Previously, only 12 patients have been reported, all of whom were diagnosed during the first prostate surgery. In this study, we report the first case of prostatic MCSRC that developed from the long course of prostatic mucinous carcinoma; the histological transformation was extremely uncommon. Because therapy of prostatic MCSRC is tricky and prognosis is worse, we share the management experience, raise awareness, and highlight the early and active treatment intervention for recurrent prostate mucinous carcinoma and prostatic MCSRC with multidisciplinary cooperation.