Case Report
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Apr 16, 2022; 10(11): 3615-3623
Published online Apr 16, 2022. doi: 10.12998/wjcc.v10.i11.3615
Contrast-enhanced ultrasound manifestations of synchronous combined hepatocellular-cholangiocarcinoma and hepatocellular carcinoma: A case report
Ling Gao, Jia-Yan Huang, Zi-Jian Lu, Qiang Lu
Ling Gao, Jia-Yan Huang, Qiang Lu, Department of Ultrasound, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
Ling Gao, Department of Ultrasound, Chengdu BOE hospital, Chengdu 610219, Sichuan Province, China
Zi-Jian Lu, Department of Pathology, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
Author contributions: Gao L reviewed the literature and drafted the article; Lu Q conceived the article; Lu Q and Huang JY provided critical revision to the manuscript; Lu ZJ contributed pathological data; and all authors issued final approval for the version to be submit.
Informed consent statement: Informed written consent was obtained from the patient’s daughter for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Qiang Lu, MD, Chief Doctor, Department of Ultrasound, West China Hospital, Sichuan University, No. 37 Guo Xue Xiang, Chengdu 610041, Sichuan Province, China. luqiang@scu.edu.cn
Received: December 12, 2021
Peer-review started: December 12, 2021
First decision: January 26, 2022
Revised: February 8, 2022
Accepted: February 23, 2022
Article in press: February 23, 2022
Published online: April 16, 2022
Processing time: 117 Days and 3 Hours
Core Tip

Core Tip: Synchronous hepatocellular-cholangiocarcinoma (CHC) and hepatocellular carcinoma (HCC) is rare and tend to be misdiagnosed as multiple HCC in clinical settings. Patients afflicted with this disorder generally have poor prognosis, moreover, preoperative imaging diagnosis is often challenging. This paper introduces contrast-enhanced ultrasound (CEUS) manifestations of a case of synchronous CHC and HCC, which showed different imaging features on CEUS images. Overall, the combination of CEUS characteristics with clinical information could help in effective diagnosis of synchronous CHC and HCC, as well as clinical decision-making and patients’ prognosis.