Case Report
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Apr 16, 2022; 10(11): 3496-3504
Published online Apr 16, 2022. doi: 10.12998/wjcc.v10.i11.3496
Preoperational diagnosis and management of breast ductal carcinoma in situ arising within fibroadenoma: Two case reports
Jun Wu, Ke-Wang Sun, Qiu-Ping Mo, Ze-Ran Yang, Yuan Chen, Miao-Chun Zhong
Jun Wu, Ke-Wang Sun, Qiu-Ping Mo, Miao-Chun Zhong, Department of Breast Surgery, Zhejiang Provincial People’s Hospital, People’s Hospital of Hangzhou Medical College, Hangzhou 310014, Zhejiang Province, China
Jun Wu, Ke-Wang Sun, Qiu-Ping Mo, Ze-Ran Yang, Yuan Chen, Miao-Chun Zhong, Cancer Center, Zhejiang Provincial People’s Hospital, People’s Hospital of Hangzhou Medical College, Hangzhou 310014, Zhejiang Province, China
Ze-Ran Yang, Yuan Chen, Department of Pathology, Zhejiang Provincial People’s Hospital, People’s Hospital of Hangzhou Medical College, Hangzhou 310014, Zhejiang Province, China
Author contributions: Zhong MC designed the report; Sun KW, Mo QP, Yang ZR and Chen Y collected the patient’s clinical data; Wu J and Zhong MC analyzed the data and wrote the paper.
Informed consent statement: The patients consented to submission of their anonymized cases and accompanying images.
Conflict-of-interest statement: The authors declare having no conflicts of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Miao-Chun Zhong, MM, Surgeon, Department of Breast Surgery, Zhejiang Provincial People’s Hospital, People’s Hospital of Hangzhou Medical College, No. 158 Shangtang Road, Hangzhou 310014, Zhejiang Province, China. zhongmiaochun@126.com
Received: August 9, 2021
Peer-review started: August 9, 2021
First decision: November 17, 2021
Revised: December 5, 2021
Accepted: February 27, 2022
Article in press: February 27, 2022
Published online: April 16, 2022
Processing time: 241 Days and 19.8 Hours
Core Tip

Core Tip: Breast ductal carcinoma in situ arising within a fibroadenoma is a rare event. We present 2 such cases and discuss their clinical and imaging findings as well as treatment. Both patients underwent breast-conserving surgery and sentinel lymph node biopsy. The 2 cases received or planned to receive radiotherapy as well as endocrine therapy (tamoxifen). More sections are needed to reduce the missed rate. Complete follow-up data with preoperative imaging can help with decision-making during patient follow-up.