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©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Apr 16, 2022; 10(11): 3334-3351
Published online Apr 16, 2022. doi: 10.12998/wjcc.v10.i11.3334
Published online Apr 16, 2022. doi: 10.12998/wjcc.v10.i11.3334
Autophagy-related long non-coding RNA prognostic model predicts prognosis and survival of melanoma patients
Yue Qiu, Department of Bone and Joint Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning 530000, Guangxi Zhuang Autonomous Region, China
Yue Qiu, Xi-Fan Zheng, Xing Huang, Jin-Zhi Meng, Jun-Pu Huang, Zhen-Pei Wen, Department of Bone and Joint Surgery, Guangxi Medical University, Nanning 530000, Guangxi Zhuang Autonomous Region, China
Hong-Tao Wang, Jun Yao, Department of Orthopedics, The First Affiliated Hospital of Guangxi Medical University, Guangxi Medical University, Nanning 530000, Guangxi Zhuang Autonomous Region, China
Author contributions: Qiu Y wrote the manuscript; Huang JP and Wen ZP contributed to data sorting; Qiu Y, Yao J, and Wang HT performed data analysis; Meng JZ, Zheng XF, and Huang X finalized the manuscript; Yao J read and approved the final manuscript.
Institutional review board statement: Institutional review board approval is not required since this study using the public datasets from the TCGA and GEO databases.
Conflict-of-interest statement: There are no conflicts or financial interests to disclose.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jun Yao, MD, Chief Doctor, Surgeon, Department of Orthopedics, The First Affiliated Hospital of Guangxi Medical University, Guangxi Medical University, No. 6 Shuangyong Road, Nanning 530000, Guangxi Zhuang Autonomous Region, China.
Received: August 10, 2021
Peer-review started: August 10, 2021
First decision: October 20, 2021
Revised: October 29, 2021
Accepted: January 17, 2022
Article in press: January 17, 2022
Published online: April 16, 2022
Processing time: 240 Days and 20.6 Hours
Peer-review started: August 10, 2021
First decision: October 20, 2021
Revised: October 29, 2021
Accepted: January 17, 2022
Article in press: January 17, 2022
Published online: April 16, 2022
Processing time: 240 Days and 20.6 Hours
Core Tip
Core Tip: Long non-coding ribonucleic acids (lncRNAs) are key factors in the development of many malignant tumors and are involved in the prognosis of some patients. The expression of autophagy-associated lncRNAs was associated with survival in melanoma patients. We obtained 15 autophagy-related lncRNAs and established a melanoma prognosis model, which can predict the prognosis of melanoma patients and is more accurate than TNM stage, age, gender, and other clinical indicators, and may provide autophagy-related clinical targets for the treatment of melanoma.