Observational Study
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Apr 6, 2022; 10(10): 3113-3120
Published online Apr 6, 2022. doi: 10.12998/wjcc.v10.i10.3113
Breast-conserving surgery and sentinel lymph node biopsy for breast cancer and their correlation with the expression of polyligand proteoglycan-1
Fu-Ming Li, Dan-Ying Xu, Qi Xu, Yan Yuan
Fu-Ming Li, Dan-Ying Xu, Qi Xu, Yan Yuan, Department of Breast Surgery, The Second Hospital of Jiaxing, Jiaxing 314000, Zhejiang Province, China
Author contributions: Li FM and Xu DY contributed equally to this work and are considered co-first authors; Li FM and Xu DY analyzed and interpreted data and wrote the manuscript; Xu Q and Yuan Y drafted the manuscript and collected the data; Li FM designed the study and revised the manuscript for important intellectual content.
Supported by Jiaxing Science and Technology Project, No. 2021AD30119.
Institutional review board statement: The study was reviewed and approved by the Jiaxing Second Hospital Institutional Review Board (Approval No. JXEY-2021JX005).
Informed consent statement: All study participants provided informed written consent prior to study enrollment.
Conflict-of-interest statement: Dr. Li FM reports grants from Jiaxing Science and Technology Project, during the conduct of the study. No other conflict-of-interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Fu-Ming Li, MHSc, Associate Chief Physician, Department of Breast Surgery, The Second Hospital of Jiaxing, No. 1518 Huancheng North Road, Nanhu District, Jiaxing 314000, Zhejiang Province, China. doclfm@163.com
Received: December 20, 2021
Peer-review started: December 20, 2021
First decision: January 18, 2022
Revised: February 6, 2022
Accepted: February 20, 2022
Article in press: February 20, 2022
Published online: April 6, 2022
Processing time: 99 Days and 1.2 Hours
Core Tip

Core Tip: Breast preservation and sentinel lymph node biopsy has shown to have a good treatment effect in patients with breast cancer, especially in older patients, as well as the significant advantage of guaranteed postoperative quality of life for patients. Polyligand proteoglycan-1 is used as a cell surface mucin polysaccharide, which is also a kind of biological macromolecular protein closely associated with tumorigenesis. In this study, we explored the relationship between breast cancer treatment and polyligand proteoglycan-1 through this study.