Bai B, Mao CS, Li Z, Kuang SL. Endoscopic ultrasonography diagnosis of gastric glomus tumors. World J Clin Cases 2021; 9(33): 10126-10133 [PMID: 34904082 DOI: 10.12998/wjcc.v9.i33.10126]
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Nov 26, 2021; 9(33): 10126-10133 Published online Nov 26, 2021. doi: 10.12998/wjcc.v9.i33.10126
Endoscopic ultrasonography diagnosis of gastric glomus tumors
Bing Bai, Chong-Shan Mao, Zhen Li, Sheng-Li Kuang
Bing Bai, Zhen Li, Oncology Center, Henan Provincial People's Hospital (People's Hospital of Zhengzhou University), Zhengzhou 450003, Henan Province, China
Chong-Shan Mao, Public Health Medical Center, Henan Provincial People's Hospital (People's Hospital of Zhengzhou University), Zhengzhou 450003, Henan Province, China
Sheng-Li Kuang, Department of Digestive Disease, Henan Provincial People's Hospital, Zhengzhou 450003, Henan Province, China
Author contributions: Bai B, Mao CS, Li Z and Kuang SL contributed equally to this work; Bai B designed the research study; Mao CS performed the case search; Li Z analyzed the data; Kuang SL wrote the manuscript; all authors have read and approved the final manuscript.
Institutional review board statement: This study was reviewed and approved by the Ethics Committee of the Henan Provincial People's Hospital.
Informed consent statement: The study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: We declare that we do not have any commercial or associative interest that represents a conflict of interest in connection with the work submitted.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Received: May 28, 2021 Peer-review started: May 28, 2021 First decision: July 1, 2021 Revised: July 3, 2021 Accepted: October 11, 2021 Article in press: October 11, 2021 Published online: November 26, 2021
ARTICLE HIGHLIGHTS
Research background
Gastric glomus tumors are relatively rare, and there is little knowledge regarding their endoscopic ultrasound findings.
Research motivation
Knowledge of the endoscopic characteristics of gastric glomus tumor is helpful in the diagnosis and differential diagnosis, and avoiding unnecessary surgery.
Research objectives
To summarize the endoscopic ultrasound characteristics of gastric glomus tumors confirmed by histopathology, and to verify the effectiveness of these characteristics in clinical cases.
Research methods
The records of 12 consecutive patients undergoing endoscopic ultrasonography (EUS) examination, surgery and pathology analysis for gastric glomus tumors in one institution from 2013-2020 were reviewed. Analysis of the EUS characteristics of gastric glomus tumors (such as tumor location, shape, size, echogenicity, homogeneity, margins, layer of origin, and so on) was carried out.
Research results
Ten cases had smooth hemispherical bulges of the mucosa, the same color as the surrounding mucosa, and 2 cases had small concave ulcers on the mucosa surface, leading to hemorrhage. The lesions were located in the anterior wall of the gastric antrum in 3 cases and in the lesser curvature of the gastric antrum in 9 cases. EUS showed that the lesions were round, ranging in maximum diameter from 10 mm to 35 mm with a mean diameter of 20 mm. The echo was slightly hypoechoic, and uniform, accompanied by small hyperechoic spots in some. There were small anechoic areas in the larger lesions, and halos with a lower echo. The outer boundary of the halo was clear, and the inner boundary was fuzzy. All of the lesions originated from the muscularis propria.
Research conclusions
Typical manifestations of gastric glomus tumors include gastric antrum location, originate from the fourth layer, solitary, round and slightly hypoechoic lesions with halos at the margins.
Research perspectives
A multi-center study, with an expanded sample size and prospective verification is required.
