Ding HJ, Ma C, Ye FP, Zhang JF. Bridging therapy and direct mechanical thrombectomy in the treatment of cardiogenic cerebral infarction with anterior circulation macrovascular occlusion. World J Clin Cases 2021; 9(27): 8051-8060 [PMID: 34621862 DOI: 10.12998/wjcc.v9.i27.8051]
Corresponding Author of This Article
Ji-Fang Zhang, MD, Chief Physician, Department of Neurosurgery, Qingdao Municipal Hospital, School of Medicine, Qingdao University, No. 1 Jiaozhou Road, Qingdao 266071, Shandong Province, China. zhangfang555@vip.163.com
Research Domain of This Article
Neurosciences
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Sep 26, 2021; 9(27): 8051-8060 Published online Sep 26, 2021. doi: 10.12998/wjcc.v9.i27.8051
Bridging therapy and direct mechanical thrombectomy in the treatment of cardiogenic cerebral infarction with anterior circulation macrovascular occlusion
Hong-Ju Ding, Cong Ma, Fu-Ping Ye, Ji-Fang Zhang
Hong-Ju Ding, Department of Emergency, Qingdao Jiaozhou Central Hospital, Qingdao 266300, Shandong Province, China
Cong Ma, Department of Neurology, Qingdao Jiaozhou Central Hospital, Qingdao 266300, Shandong Province, China
Fu-Ping Ye, Department of Gastrointestinal Surgery, Qingdao Jiaozhou Central Hospital, Qingdao 266300, Shandong Province, China
Ji-Fang Zhang, Department of Neurosurgery, Qingdao Municipal Hospital, School of Medicine, Qingdao University, Qingdao 266071, Shandong Province, China
Author contributions: Ding HJ, Ma C, Ye FP and Zhang JF designed the research study; Ding HJ and Zhang JF performed the research; Ma C contributed new reagents and analytic tools; Ye FP analyzed the data and wrote the manuscript; all authors have read and approve the final manuscript.
Institutional review board statement: The study was reviewed and approved by the Qingdao Jiaozhou Central Hospital Institutional Review Board (Approval No. 20FD8731).
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: No conflict of interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ji-Fang Zhang, MD, Chief Physician, Department of Neurosurgery, Qingdao Municipal Hospital, School of Medicine, Qingdao University, No. 1 Jiaozhou Road, Qingdao 266071, Shandong Province, China. zhangfang555@vip.163.com
Received: May 18, 2021 Peer-review started: May 18, 2021 First decision: June 15, 2021 Revised: June 29, 2021 Accepted: August 5, 2021 Article in press: August 5, 2021 Published online: September 26, 2021
ARTICLE HIGHLIGHTS
Research background
Cardiogenic cerebral infarction is an important pathological type of cerebral infarction.
Research motivation
The difference between direct mechanical thrombectomy and bridging therapy in treating cerebral infarction with anterior circulation macrovascular occlusion still needs to be further explored and confirmed.
Research objectives
This study aimed to investigate the efficacy and safety of bridging therapy and direct mechanical thrombectomy in the treatment of cardiogenic cerebral infarction with anterior circulation macrovascular occlusion.
Research methods
Total 96 patients with cardiogenic cerebral infarction with anterior circulation macrovascular occlusion were retrospectively selected and divided into a direct thrombectomy group and a bridging group according to the treatment plan.
Research results
There was no significant difference in the recanalization rate between the direct thrombectomy group and the bridging group.
Research conclusions
Bridging therapy and direct mechanical thrombectomy for the treatment of cardiogenic cerebral infarction with anterior circulation macrovascular occlusion can achieve good vascular recanalization effects and improve the prognosis and neurological function of patients.
Research perspectives
Whether the research results can be broadly generalized still needs to be further investigated and confirmed by expanding the sample selection range and increasing the sample size.
