Retrospective Study
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Sep 26, 2021; 9(27): 8027-8034
Published online Sep 26, 2021. doi: 10.12998/wjcc.v9.i27.8027
Accuracy of ultrasonography in diagnosis of fetal central nervous system malformation
Bo Pang, Jing-Jing Pan, Qin Li, Xia Zhang
Bo Pang, Xia Zhang, Department of Ultrasound, The First Affiliated Hospital of Wannan Medical College, Wuhu 241000, Anhui Province, China
Jing-Jing Pan, Department of Neurosurgery, The Second People’s Hospital of Wuhu, Wuhu 241000, Anhui Province, China
Qin Li, Department of Gynaecology and Obstetrics, The First Affiliated Hospital of Wannan Medical College, Wuhu 241000, Anhui Province, China
Author contributions: Pang B and Zhang X designed this retrospective study; Pan JJ wrote this paper; Li Q was responsible for sorting the data.
Supported by the Research Project on Application of Commonweal Technology in Anhui Province, No. 1704f0804048.
Institutional review board statement: The study was reviewed and approved by The First Affiliated Hospital of Wannan Medical College Institutional Review Board.
Informed consent statement: Informed consent was obtained from the patient.
Conflict-of-interest statement: No conflict of interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Corresponding author: Xia Zhang, MHSc, Chief Physician, Department of Ultrasound, The First Affiliated Hospital of Wannan Medical College, No. 2 Zheshan West Road, Wuhu 241000, Anhui Province, China.
Received: April 15, 2021
Peer-review started: April 15, 2021
First decision: May 11, 2021
Revised: May 18, 2021
Accepted: July 23, 2021
Article in press: July 23, 2021
Published online: September 26, 2021
Research background

Birth defects are abnormalities in the fetal body structure and function that occur in the uterus before delivery.

Research motivation

It is necessary to diagnose birth defects as efficiently and accurately as possible.

Research objectives

This study aimed to determine the application value of ultrasonography examination.

Research methods

One hundred and thirteen pregnant women suspected of having fetal central nervous system (CNS) malformations at our hospital from December 2018 to October 2020 were examined using two-dimensional ultrasonography and three-dimensional ultrasonography, respectively.

Research results

The diagnostic sensitivity (92.41%) and accuracy (91.15%) of three-dimensional ultrasonography were higher than those of two-dimensional ultrasonography (64.56% and 68.14%, respectively).

Research conclusions

Three-dimensional ultrasonography has high application value in the diagnosis of fetal CNS malformations.

Research perspectives

Screening of birth defects is important in the clinic.