Published online Sep 16, 2021. doi: 10.12998/wjcc.v9.i26.7762
Peer-review started: April 13, 2021
First decision: May 11, 2021
Revised: May 16, 2021
Accepted: July 22, 2021
Article in press: July 22, 2021
Published online: September 16, 2021
Postoperative ileus (POI) is a perplexing problem for clinical surgeons. POI occurs not only after abdominal surgery, but also after any other surgery that requires general anesthesia.
Regarding enhanced recovery after surgery, postoperative gastrointestinal function recovery is of great concern. Currently, there is an urgent need to improve posto
This study aimed to observe whether dexmedetomidine (DEX) promotes bowel movements in patients after laparoscopic nephrectomy
A total of 120 patients who underwent laparoscopic nephrectomy were assigned into three groups: C (normal saline infusion), D1 (DEX 0.02 µg/kg/h), and D2 (DEX 0.04 µg/kg/h).
Mean blood pressure (MBP) at T1 in groups D1 and D2 was significantly lower than that in group C. MBP was lower than the baseline at T2, T3, T4, and T5 in group C, and at T1 and T4 in groups D1 and D2.
Perioperative DEX infusion at 0.04 µg/kg/h resulted in better and faster recovery of gastrointestinal function and a more favorable analgesic effect without additional adverse effects in patients who underwent laparoscopic nephrectomy.
This study suggests a new method for postoperative intestinal function recovery.