Retrospective Study
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Sep 6, 2021; 9(25): 7358-7364
Published online Sep 6, 2021. doi: 10.12998/wjcc.v9.i25.7358
Characteristic analysis of clinical coronary heart disease and coronary artery disease concerning young and middle-aged male patients
Kai-Ge Peng, Hui-Lin Yu
Kai-Ge Peng, Hui-Lin Yu, Department of Cardiovascular Medicine, Anqing Municipal Hospital, Anqing 230032, Anhui Province, China
Author contributions: Peng KG designed the experiment; Yu HL drafted the work; Peng KG collected the data; Yu HL analyzed and interpreted data; Peng KG and Yu HL wrote the article.
Institutional review board statement: This study was approved by the Anqing Municipal Hospital Ethics Committee.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Kai-Ge Peng, MD, Associate Chief Physician, Department of Cardiovascular Medicine, Anqing Municipal Hospital, No. 802 Building B, Xinhui Plaza, Yanjiang West Road, Yingjiang District, Anqing 230032, Anhui Province, China. xpgdd11@sina.com
Received: March 18, 2021
Peer-review started: March 18, 2021
First decision: April 23, 2021
Revised: May 15, 2021
Accepted: July 9, 2021
Article in press: July 9, 2021
Published online: September 6, 2021
ARTICLE HIGHLIGHTS
Research background

Coronary heart disease (CHD) is a type of coronary atherosclerotic heart disease. In recent years, the incidence of CHD has increased annually, and the age of onset has gradually decreased. Severe CHD may cause severe myocardial ischemia or myocardial necrosis, which in turn may cause myocardial infarction and related complications, with serious consequences.

Research motivation

Because CHD occurs in young people, the impact on the quality of life of young patients after the disease, labor loss, and prognosis are much greater than that of middle-aged patients. The clinical features and risk factors of young patients have been characterized, and we hope to explore this.

Research objectives

This study aimed to analyze the clinical characteristics of coronary artery disease in young and middle-aged men with CHD.

Research methods

A total of 110 male CHD patients were selected as research subjects and then divided into two groups by age: a middle-aged group (n = 55) and a young group (n = 55). The coronary arteries and clinical features of the patients were compared.

Research results

In the young group, age, diabetes, hypertension, smoking history, body mass index, family history of CHD, drinking history, fibrinogen, low-density lipoprotein cholesterol, total cholesterol, and single-vessel disease (SVD) were higher in the young group than in the middle-aged group. The middle-aged group mainly suffered from a high Gensini score, implicating multiple arteries, whereas the young group was mainly affected by SVD. The between-group differences were significant.

Research conclusions

In CHD attacks, multiple coronary arteries are implicated in middle-aged male patients, whereas SVD is implicated in young male patients.

Research perspectives

In middle-aged and elderly male patients, multiple coronary arteries are involved in CHD attacks, while in young male patients it is associated with SVD, which has certain hints for subsequent clinical diagnosis and treatment.