Retrospective Study
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Sep 6, 2021; 9(25): 7358-7364
Published online Sep 6, 2021. doi: 10.12998/wjcc.v9.i25.7358
Characteristic analysis of clinical coronary heart disease and coronary artery disease concerning young and middle-aged male patients
Kai-Ge Peng, Hui-Lin Yu
Kai-Ge Peng, Hui-Lin Yu, Department of Cardiovascular Medicine, Anqing Municipal Hospital, Anqing 230032, Anhui Province, China
Author contributions: Peng KG designed the experiment; Yu HL drafted the work; Peng KG collected the data; Yu HL analyzed and interpreted data; Peng KG and Yu HL wrote the article.
Institutional review board statement: This study was approved by the Anqing Municipal Hospital Ethics Committee.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Kai-Ge Peng, MD, Associate Chief Physician, Department of Cardiovascular Medicine, Anqing Municipal Hospital, No. 802 Building B, Xinhui Plaza, Yanjiang West Road, Yingjiang District, Anqing 230032, Anhui Province, China. xpgdd11@sina.com
Received: March 18, 2021
Peer-review started: March 18, 2021
First decision: April 23, 2021
Revised: May 15, 2021
Accepted: July 9, 2021
Article in press: July 9, 2021
Published online: September 6, 2021
Processing time: 165 Days and 22.4 Hours
Abstract
BACKGROUND

Coronary heart disease (CHD) is a type of coronary atherosclerotic heart disease. In recent years, the incidence of CHD has been increasing annually, with an increasing number of young patients. Severe CHD may cause severe myocardial ischemia or myocardial necrosis, which in turn may cause myocardial infarction and related complications that seriously affect the life and health of the patient.

AIM

To examine the coronary arteries and clinical features of young and middle-aged male patients with CHD.

METHODS

From February 2019 to January 2020, 110 male CHD patients admitted to our hospital were selected as research subjects and were divided into two groups by age: middle-aged group (n = 55) and young group (n = 55). The coronary arteries and clinical features of the patients were compared.

RESULTS

There were no significant differences in dyslipidemia, stroke history, high-density lipoprotein cholesterol, or triacylglycerol (P > 0.05) between the two groups. In the young group, age, diabetes, hypertension, smoking history, body mass index, family history of CHD, drinking history, fibrinogen, low-density lipoprotein cholesterol, total cholesterol, and single-vessel disease were higher than those in the middle-aged group. Correspondingly, serum uric acid, hyperuricemia, myocardial infarction, Gensini score > 50, collateral circulation, multivessel disease, double vessel disease, involvement of the right coronary artery, and involvement of the left main coronary artery were lower in the young group than in the middle-aged group. The middle-aged group mainly suffered from a high Gensini score, implicating multiple arteries, whereas the young group was mainly affected by single-vessel disease. The between-group difference was significant (P < 0.05).

CONCLUSION

In CHD attacks, multiple coronary arteries are implicated in middle-aged male patients and single-vessel disease in young male patients.

Keywords: Coronary heart disease; Coronary artery disease; Coronary artery features; Myocardial ischemia; Risk factors

Core Tip: Retrospective studies have confirmed the involvement of multiple coronary arteries in the onset of coronary heart disease (CHD) in middle-aged and elderly male patients and in single-vessel disease in young male patients. This study included 110 male CHD patients as research cases to examine the coronary arteries and clinical features of young and middle-aged male CHD patients.