Case Control Study
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jul 6, 2021; 9(19): 5028-5036
Published online Jul 6, 2021. doi: 10.12998/wjcc.v9.i19.5028
Efficacy of Solitaire AB stent-release angioplasty in acute middle cerebral artery atherosclerosis obliterative cerebral infarction
Xi-Feng Wang, Ming Wang, Gang Li, Xue-Yu Xu, Wei Shen, Jing Liu, Shuang-Shuang Xiao, Jiang-Hong Zhou
Xi-Feng Wang, Ming Wang, Gang Li, Xue-Yu Xu, Wei Shen, Jing Liu, Shuang-Shuang Xiao, Jiang-Hong Zhou, Department of Neurology, Puai Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430033, Hubei Province, China
Author contributions: Wang XF, Wang M and Li G designed the research; Xu XY, Shen W and Liu J performed the research; Liu J and Xiao SS contributed new reagents/analytic tools; Wang XF analyzed the data; Wang XF and Zhou JH wrote the paper.
Institutional review board statement: The study was reviewed and approved by the Puai Hospital, Tongji Medical College, Huazhong University of Science and Technology Institutional Review Board.
Informed consent statement: Informed written consent was obtained from the patients.
Conflict-of-interest statement: No one at any time received payment or services from a third party (government, commercial, private foundation, etc.) for any aspect of the submitted work (including but not limited to grants, data monitoring board, study design, manuscript preparation, statistical analysis). No one has financial relationships (regardless of amount of compensation) with entities as described in the instructions during the 36 mo prior to publication.
STROBE statement: The authors have read the STROBE statement, and the manuscript was prepared and revised according to the STROBE statement.
Data sharing statement: Technical appendix, statistical code, and dataset available from the corresponding author at 815107426@qq.com.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jiang-Hong Zhou, MSc, Professor, Department of Neurology, Puai Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 76 Jiefang Avenue, Qiaokou District, Wuhan 430033, Hubei Province, China. 815107426@qq.com
Received: March 2, 2021
Peer-review started: March 2, 2021
First decision: April 4, 2021
Revised: April 10, 2021
Accepted: April 20, 2021
Article in press: April 20, 2021
Published online: July 6, 2021
Processing time: 113 Days and 22.5 Hours
ARTICLE HIGHLIGHTS
Research background

In recent years, the application of various intravascular thrombectomy devices has led to the rapid development of intravascular therapy, the Solitaire AB is a recyclable stent and its efficacy has been confirmed in several large clinical trials. Stent thrombectomy in the treatment of aortic occlusion was rapidly recommended as the standard treatment for acute great artery occlusion by domestic and international guidelines. However, the etiology of acute aortic occlusive cerebral infarction is complex, and at present, there is relatively little research on different treatment strategies for different etiologies and pathogenesis.

Research motivation

Aimed at the characteristics of intracranial atherosclerotic occlusion as the main pathogenesis of acute cerebral infarction in domestic patients, targeted treatment is required.

Research objectives

To analyze the safety and efficacy of Solitaire AB stent-release angioplasty in patients with acute middle cerebral artery atherosclerosis obliterative cerebral infarction.

Research methods

To observe the effect of Solitaire AB stent release in 25 patients with acute middle cerebral artery atherosclerotic cerebral infarction enrolled in a retrospective study.

Research results

The operation was successful in all 25 patients, the mean recanalization time was 23 min, the National Institutes of Health Stroke Scale scores decreased significantly at different time points after surgery, and the proportion of patients with a 3 mo modified Rankin scale score ≤ 2 was 80%.

Research conclusions

For patients with acute anterior circulation occlusion caused by intracranial aortic artery atherosclerosis, after Solitaire AB stent opening if the forward flow can maintain the level of modified thrombolysis in cerebral infarction 2b/3, stent release may be safe and effective.

Research perspectives

From the perspective of clinical practice, according to the main causes of acute aortic occlusion in China, targeted treatment methods should be adopted.