Wang Y, Hou ZJ, Wang HZ, Hu M, Li YX, Zhang Z. Comparison of ocular axis and corneal diameter between entropion and non-entropion eyes in children with congenital glaucoma. World J Clin Cases 2021; 9(18): 4637-4643 [PMID: 34222430 DOI: 10.12998/wjcc.v9.i18.4637]
Corresponding Author of This Article
Yue Wang, MD, Associate Chief Physician, Department of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital of Capital Medical University, Beijing Key Laboratory of Ophthalmology and Visual Science, No. 1 Dongjiaominxiang, Dongcheng District, Beijing 100730, China. nickwang8672@sina.com
Research Domain of This Article
Ophthalmology
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Yue Wang, Zhi-Jia Hou, Huai-Zhou Wang, Yu-Xin Li, Zheng Zhang, Department of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital of Capital Medical University, Beijing Key Laboratory of Ophthalmology and Visual Science, Beijing 100730, China
Man Hu, National Key Discipline of Pediatrics, Ministry of Education, Department of Ophthalmology, Beijing Children’s Hospital, Capital Medical University, Beijing 100045, China
Author contributions: Wang Y design the study; Hou ZJ and Wang HZ drafted the work; Hu M and Wang HZ collected the data; Li YX and Zhang Z analyzed and interpreted the data; Wang Y and Wang HZ wrote the article.
Institutional review board statement: The study was reviewed and approved by the Beijing Tongren Hospital Institutional Review Board.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: None of the authors has a financial interest in any of the products, devices, or drugs mentioned in this manuscript.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yue Wang, MD, Associate Chief Physician, Department of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital of Capital Medical University, Beijing Key Laboratory of Ophthalmology and Visual Science, No. 1 Dongjiaominxiang, Dongcheng District, Beijing 100730, China. nickwang8672@sina.com
Received: April 8, 2021 Peer-review started: April 8, 2021 First decision: April 28, 2021 Revised: May 7, 2021 Accepted: May 19, 2021 Article in press: May 19, 2021 Published online: June 26, 2021 Processing time: 64 Days and 0.5 Hours
ARTICLE HIGHLIGHTS
Research background
Children with congenital glaucoma are often accompanied by acquired epiblepharon in the lower eyelid, which causes entropion of the lower eyelid and damages the cornea. Few studies have evaluated the ocular axis and corneal diameter of acquired epiblepharon in patients with congenital glaucoma.
Research motivation
Acquired epiblepharon in patients with congenital glaucoma could affect the development of vision and quality of life. Children with congenital glaucoma are easy to accompany with acquired epiblepharon.
Research objectives
This study aimed to infer the possible causes of lower eyelid entropion by comparing the difference of ocular axis and corneal diameter between inverted and non-inverted ciliary eyes in children with congenital glaucoma.
Research methods
A total of 15 patients, including five with bilateral glaucoma and ten with unilateral glaucoma, only had one eye with lower eyelid entropion associated with congenital glaucoma. Main outcome measures were the ocular axis and corneal diameter.
Research results
The average ocular axis of congenital glaucoma eyes with lower eyelid entropion was 24.86 ± 3.44 mm and without lower eyelid entropion was 20.79 ± 1.34 mm. The average corneal diameter of congenital glaucoma eye with lower eyelid entropion was 13.61 ± 0.88 mm and without lower eyelid entropion was 11.63 ± 0.48 mm.
Research conclusions
The rapid growth of ocular axis and corneal diameter may be the main cause of congenital glaucoma with acquired lower eyelid entropion.
Research perspectives
Children with poor control of intraocular pressure and excessive growth of the ocular axis and corneal diameter must be observed for the existence of acquired epiblepharon. This study was limited by its size. A prospective study with a large sample size and long-term follow-up is needed.
