Retrospective Study
Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Dec 6, 2020; 8(23): 5894-5901
Published online Dec 6, 2020. doi: 10.12998/wjcc.v8.i23.5894
Application value analysis of magnetic resonance imaging and computed tomography in the diagnosis of intracranial infection after craniocerebral surgery
Lan Gu, Xiao-Liang Yang, Hui-Kang Yin, Ze-Hua Lu, Cheng-Jun Geng
Lan Gu, Department of Radiology, Wuxi Fifth People’s Hospital, Wuxi 214000, Jiangsu Province, China
Xiao-Liang Yang, Hui-Kang Yin, Ze-Hua Lu, Cheng-Jun Geng, Department of Medical Imaging, Wuxi Medical College of Anhui Medical University, 904th Hospital of Joint Logistic Support Force of PLA, Wuxi 214044, Jiangsu Province, China
Author contributions: Gu L and Yang XL contributed equally to this article and should be considered as co-first authors; Gu L and Yang XL designed this retrospective study; Yin HK wrote the paper; Lu ZH was responsible for collating the data.
Institutional review board statement: The study was reviewed and approved by The 904th Hospital of the Joint Logistics Support Force of the Chinese PLA General Hospital Institutional Review Board (Approval No. 2016-03-01). 
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data.
Conflict-of-interest statement: Lan Gu has received fees for serving as a speaker.
Data sharing statement: Technical appendix, statistical code, and dataset available from the corresponding author at 1092764537@qq.com. Participants gave informed consent for data sharing.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Cheng-Jun Geng, MHSc, Associate Chief Physician, Department of Medical Imaging, Wuxi Medical College of Anhui Medical University, 904th Hospital of Joint Logistic Support Force of PLA, No. 101 Xingyuan North Road, Wuxi 214044, Jiangsu Province, China. hfgcj@yeah.net
Received: June 16, 2020
Peer-review started: June 16, 2020
First decision: July 25, 2020
Revised: August 11, 2020
Accepted: October 19, 2020
Article in press: October 19, 2020
Published online: December 6, 2020
Processing time: 170 Days and 22.7 Hours
ARTICLE HIGHLIGHTS
Research background

Intracranial infection is a common clinical disease and a common complication after craniocerebral surgery. In recent years, there have been advances in clinical head computed tomography (CT) and magnetic resonance imaging (MRI) examinations of the temporal lobe to visualize focal hemorrhagic brain tissue.  

Research motivation

To study the application value of MRI and CT in the diagnosis of intracranial infection after craniocerebral surgery and improve the diagnosis rate of intracranial infection.

Research objectives

This study determined the diagnostic value of MRI and CT for intracranial infection after craniocerebral surgery.

Research methods

We selected 82 patients who underwent craniocerebral surgery. All 82 patients received CT and MRI examinations, and a retrospective analysis was performed. The coincidence rate of positive diagnosis and the overall diagnosis coincidence rate of different pathogenic infection types were measured with the two examination methods.

Research results

MRI scans had higher positive diagnostic coincidence rates than CT scans; the overall diagnostic coincidence rate, sensitivity, specificity, positive predictive value, and negative predictive value were significantly higher with MRI examinations than with CT examinations, and the differences were statistically significant (P < 0.05).

Research conclusions

MRI can diagnose intracranial infections after clinical craniocerebral surgery more accurately than CT.

Research perspectives

To further compare the difference between CT and MRI in the diagnosis of brain diseases.