Xu P, Wu M, Yang M, Xiao J, Ruan ZM, Wu LY. Evaluation of internal and shell stiffness in the differential diagnosis of breast non-mass lesions by shear wave elastography. World J Clin Cases 2020; 8(12): 2510-2519 [PMID: 32607328 DOI: 10.12998/wjcc.v8.i12.2510]
Corresponding Author of This Article
Mei Wu, MD, Chief Doctor, Department of Ultrasound, The Second Hospital of Shandong University, No.247 Beiyuan Ave, Jinan 250033, Shandong Province, China. a_may0212@163.com
Research Domain of This Article
Radiology, Nuclear Medicine & Medical Imaging
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Jun 26, 2020; 8(12): 2510-2519 Published online Jun 26, 2020. doi: 10.12998/wjcc.v8.i12.2510
Evaluation of internal and shell stiffness in the differential diagnosis of breast non-mass lesions by shear wave elastography
Ping Xu, Mei Wu, Min Yang, Juan Xiao, Zheng-Min Ruan, Lan-Ying Wu
Ping Xu, Min Yang, Lan-Ying Wu, Department of Ultrasound, Beijing Shijitan Hospital Affiliated to Capital Medical University, Beijing 100038, China
Mei Wu, Zheng-Min Ruan, Department of Ultrasound, The Second Hospital of Shandong University, Jinan 250033, Shandong Province, China
Juan Xiao, Evidence-based Medicine Center, The Second Hospital of Shandong University, Jinan 250033, Shandong Province, China
Author contributions: Xu P, Wu M and Yang M wrote the manuscript; Wu M and Yang M designed the research; Xu P, Ruan ZM and Wu LY performed ultrasound examinations; Xu P and Xiao J analyzed the data. All authors participated in performing the research.
Institutional review board statement: This study was reviewed and approved by the Ethics Committee of The Second Hospital of Shandong University.
Informed consent statement: All patients were informed of the purpose and risk of the examination and signed an informed consent prior to ultrasonic guidance breast biopsy.
Conflict-of-interest statement: All authors declare no conflicts-of-interest related to this article.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Mei Wu, MD, Chief Doctor, Department of Ultrasound, The Second Hospital of Shandong University, No.247 Beiyuan Ave, Jinan 250033, Shandong Province, China. a_may0212@163.com
Received: February 24, 2020 Peer-review started: February 24, 2020 First decision: March 24, 2020 Revised: April 9, 2020 Accepted: April 24, 2020 Article in press: April 24, 2020 Published online: June 26, 2020
ARTICLE HIGHLIGHTS
Research background
Shear wave elastography can help the differential diagnosis of breast lesions by evaluating the hardness of breast lesions; however, there are few studies on the evaluation of the elasticity of breast non-mass lesions. In recent years, studies have shown that the evaluation of peripheral elasticity of breast lesions may have better diagnostic efficacy than other parameters. However, there has been no study on the internal and peripheral elasticity of breast non-mass lesions.
Research motivation
The aim of this study was to evaluate the internal and peripheral elasticity of breast non-mass lesions using shear wave elastography.
Research objectives
To determine the value of shear wave elastography in the differential diagnosis of non-mass breast lesions.
Research methods
The peripheral (the shell of 1 mm, 1.5 mm, 2 mm, 2.5 mm and 3 mm around the lesions) and internal elasticity of non-mass breast lesions in 118 cases were evaluated. ROC curves of each parameter were drawn and the diagnostic efficacy of each parameter was compared.
Research results
The “stiff rim” sign and other quantitative parameters within and around the breast NMLs had good diagnostic efficiency. Emax of peripheral shells had better evaluation efficiency.
Research conclusions
Combining qualitative and quantitative analyses of both internal and shell stiffness may further improve the diagnostic efficiency of breast non-mass lesions.
Research perspectives
In this study, we focused on the influence of the stiffness of the peripheral shell in breast non-mass lesions on diagnosis.
