Zhu T, Xi XY, Dong HJ. Isolated myeloid sarcoma in the pancreas and orbit: A case report and review of literature. World J Clin Cases 2018; 6(11): 477-482 [PMID: 30294614 DOI: 10.12998/wjcc.v6.i11.477]
Corresponding Author of This Article
Hong-Juan Dong, MAMS, Chief Doctor, Department of Haematology, Xijing Hospital, the Military Medical University of the PLA Air Force, No.127, Changle west road, Xincheng district, Xi’an 710032, Shaanxi Province, China. dhongjuanyahoo@163.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Oct 6, 2018; 6(11): 477-482 Published online Oct 6, 2018. doi: 10.12998/wjcc.v6.i11.477
Isolated myeloid sarcoma in the pancreas and orbit: A case report and review of literature
Ting Zhu, Xu-Yan Xi, Hong-Juan Dong
Ting Zhu, Department of Digestive Disease, Weinan Central Hospital, Weinan 714000, Shaanxi Province, China
Xu-Yan Xi, Department of Surgical Oncology, Weinan Central Hospital, Weinan 714000, Shaanxi Province, China
Hong-Juan Dong, Department of Haematology, Xijing Hospital, the Military Medical University of the PLA Air Force, Xi’an 710032, Shaanxi Province, China
Author contributions: Zhu T participated in the design of the report, analysed the data, and wrote the paper; Xi XY collected the medical imaging materials; Dong HJ designed the report and performed the preliminary revision of the article.
Informed consent statement: Consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
Open-Access: This article is an open-access article, which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Hong-Juan Dong, MAMS, Chief Doctor, Department of Haematology, Xijing Hospital, the Military Medical University of the PLA Air Force, No.127, Changle west road, Xincheng district, Xi’an 710032, Shaanxi Province, China. dhongjuanyahoo@163.com
Received: June 11, 2018 Peer-review started: June 11, 2018 First decision: June 20, 2018 Revised: July 30, 2018 Accepted: August 12, 2018 Article in press: August 12, 2018 Published online: October 6, 2018 Processing time: 110 Days and 0.8 Hours
ARTICLE HIGHLIGHTS
Case characteristics
A 36-year-old male with symptoms of recurrent abdominal pain and intermittent right eyelid oedema exhibiting space-occupying lesions in the pancreas and orbit.
Clinical diagnosis
Isolated myeloid sarcoma.
Differential diagnosis
Pancreatitis, pancreatic cancer, and lymphoma should be excluded.
Laboratory diagnosis
Normal tumour marker levels, slightly elevated liver and pancreatic enzymes, and normal routine blood and autoantibody test results.
Pathological diagnosis
A malignant tumour positive for Ki-67 (+ 80%), P53 (approximately 50%), CD43, and MPO was indicated.
Treatment
Chemotherapy combined with radiochemotherapy.
Related reports
A case of isolated myeloid sarcoma occurring simultaneously in the pancreas and orbit has never been reported.
Term explanation
Isolated myeloid sarcoma.
Experiences and lessons
This case contributes to deepening our understanding of the diagnosis of isolated myeloid sarcoma. We should combine various laboratory test results, especially pathologic and immunohistochemical results, to assist in diagnosis. Surgery is not recommended for these cases, and minimally invasive methods are preferred for pathological examinations because surgery may delay treatment and affect the prognosis of patients. In addition, we should have a sense of differentiation for atypical cases, and the monism explanation should be considered first for multi-site lesions.
