Zhu T, Xi XY, Dong HJ. Isolated myeloid sarcoma in the pancreas and orbit: A case report and review of literature. World J Clin Cases 2018; 6(11): 477-482 [PMID: 30294614 DOI: 10.12998/wjcc.v6.i11.477]
Corresponding Author of This Article
Hong-Juan Dong, MAMS, Chief Doctor, Department of Haematology, Xijing Hospital, the Military Medical University of the PLA Air Force, No.127, Changle west road, Xincheng district, Xi’an 710032, Shaanxi Province, China. dhongjuanyahoo@163.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Oct 6, 2018; 6(11): 477-482 Published online Oct 6, 2018. doi: 10.12998/wjcc.v6.i11.477
Isolated myeloid sarcoma in the pancreas and orbit: A case report and review of literature
Ting Zhu, Xu-Yan Xi, Hong-Juan Dong
Ting Zhu, Department of Digestive Disease, Weinan Central Hospital, Weinan 714000, Shaanxi Province, China
Xu-Yan Xi, Department of Surgical Oncology, Weinan Central Hospital, Weinan 714000, Shaanxi Province, China
Hong-Juan Dong, Department of Haematology, Xijing Hospital, the Military Medical University of the PLA Air Force, Xi’an 710032, Shaanxi Province, China
Author contributions: Zhu T participated in the design of the report, analysed the data, and wrote the paper; Xi XY collected the medical imaging materials; Dong HJ designed the report and performed the preliminary revision of the article.
Informed consent statement: Consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
Open-Access: This article is an open-access article, which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Hong-Juan Dong, MAMS, Chief Doctor, Department of Haematology, Xijing Hospital, the Military Medical University of the PLA Air Force, No.127, Changle west road, Xincheng district, Xi’an 710032, Shaanxi Province, China. dhongjuanyahoo@163.com
Received: June 11, 2018 Peer-review started: June 11, 2018 First decision: June 20, 2018 Revised: July 30, 2018 Accepted: August 12, 2018 Article in press: August 12, 2018 Published online: October 6, 2018 Processing time: 110 Days and 0.8 Hours
Abstract
Myeloid sarcoma (MS) is a type of extramedullary solid haematological tumour. Myeloid sarcoma is classified into two types based on whether onset of the disease is complicated by haematologic diseases: extramedullary infiltration of leukaemia (leukaemic MS) and isolated myeloid sarcoma. The incidence of isolated myeloid sarcoma is low. In particular, isolated myeloid sarcoma involving the pancreas is extremely rare and prone to misdiagnosis. This case report describes the long and eventful diagnostic process of a case of myeloid sarcoma involving the pancreas and orbit. Due to a lack of typical clinical manifestations and imaging characteristics, the patient underwent several rounds of treatment without a confirmed diagnosis. Eventually, the final diagnosis was pathologically confirmed using several types of biopsies and immunohistochemical detection. To date, this type of disease has not been reported in the literature. This case report describes the detailed diagnostic process and discusses the strategies used for diagnosis, which will facilitate the diagnosis of such diseases in the future.
Core tip: Although isolated myeloid sarcoma is difficult to diagnose, multi-site lesions provide indications for diagnosis. This case report describes isolated myeloid sarcoma occurring in both the pancreas and the orbit.
