Hu XY, Yang Q, Guan XY, Li JY, Wang LL, Li K, Zhang XT. Efficacy of surgical resection and ultra-reduced tension suture combined with superficial radiation in keloid treatment. World J Clin Cases 2023; 11(35): 8310-8319 [PMID: 38130623 DOI: 10.12998/wjcc.v11.i35.8310]
Corresponding Author of This Article
Xiao-Tao Zhang, MM, Chief Physician, Department of Radiation Oncology, The Affiliated Qingdao Central Hospital of Qingdao University, No. 127 Siliunan Road, Qingdao 266042, Shandong Province, China. xiaotaozhangdr@yeah.net
Research Domain of This Article
Dermatology
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Xiao-Ying Hu, Qiao Yang, Xiao-Yu Guan, Ling-Ling Wang, Kun Li, Department of Cosmetic Medicine, Qingdao Eighth People’s Hospital, Qingdao 266100, Shandong Province, China
Jin-Ying Li, Xiao-Tao Zhang, Department of Radiation Oncology, The Affiliated Qingdao Central Hospital of Qingdao University, Qingdao 266042, Shandong Province, China
Author contributions: Hu XY designed and performed the research and wrote the paper; Zhang XT designed the research and supervised the report; Yang Q, Guan XY, and Li JY organized the materials; Wang LL and Li K contributed to the analysis; All authors have approved the manuscript.
Supported byQingdao Medical Research Guidance Program Project, No. 2020-WJZD110.
Institutional review board statement: This study was reviewed and approved by the Ethics Committee of Qingdao Eighth People’s Hospital (Approval no.: QBYLL-KY-2023-013).
Informed consent statement: This retrospective study used only anonymous patient data. The patient signed an informed consent form for treatment before surgery, and according to institutional policies, informed consent for this study was waived.
Conflict-of-interest statement: All the authors declare no conflicts of interest related to this article.
Data sharing statement: The datasets used and/or analyzed during the current study are available from the corresponding author upon reasonable request.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xiao-Tao Zhang, MM, Chief Physician, Department of Radiation Oncology, The Affiliated Qingdao Central Hospital of Qingdao University, No. 127 Siliunan Road, Qingdao 266042, Shandong Province, China. xiaotaozhangdr@yeah.net
Received: November 10, 2023 Peer-review started: November 10, 2023 First decision: November 22, 2023 Revised: December 1, 2023 Accepted: December 6, 2023 Article in press: December 6, 2023 Published online: December 16, 2023 Processing time: 34 Days and 2.1 Hours
ARTICLE HIGHLIGHTS
Research background
Keloids are a type of pathological scar whose appearance increases the psychological burden to patients; however, in more severe cases, keloids can affect the patient’s body function, disrupting their ability to lead a normal life and even isolating them from society. When treating keloids, a unimodal treatment strategy cannot achieve significant and lasting effects; therefore, the identification of more effective treatment methods is of great significance.
Research motivation
Surgical treatment is the modality that achieves the most visible improvement; however, because of the high postoperative recurrence rate, ensuring the effect of the operation and limiting the recurrence rate is crucial. Therefore, this study is based on the well-established single treatment in the department, which can provide safe and effective comprehensive treatment, using cutting-edge super reduction suture technology and radiotherapy equipment, organic combination of surgical treatment, radiotherapy, surgical removal of keloid, super reduction suture combined with shallow radiotherapy, comprehensive treatment, according to the observation of comprehensive treatment of keloid, to elucidate.
Research objectives
To investigate the optimal scheme for adjuvant surgical treatment of keloids and improve clinical efficacy and patient satisfaction.
Research methods
The suture techniques employed in this investigation are the relatively new LBD suture and Zhang's suture. The ultra-reduced tension suture was placed once the subcutaneous surface of the wound edge was completely free. This study selected several radiotherapy strategies approved in the field to guarantee optimal results; however, all were performed within 24 h of surgery. The Scar Observation Scale of the patient and observer was completed concurrently during the same observation period, considering both patients' subjective experiences and professionals' objective indicators.
Research results
This study’s findings demonstrate that maximum resection, super tension suture, and superficial radiotherapy administered within 24 h of surgery can achieve a beneficial effect and ensure a low recurrence rate for keloids congruent with surgical justifications.
Research conclusions
Surgical treatment of keloid is the traditional therapeutic modality. This study uses a more cutting-edge tension suture technique. Surgical resection, super subtraction sutures, and superficial radiotherapy are treatment methods with short courses, low recurrence rates, and good safety profiles.
Research perspectives
Future studies should observe more cases as treatment options mature. Simultaneously, patients who select surgery and other methods, such as botulinum toxin, platelet-rich plasma, and nano-fat injections, could be selected as other observation groups to seek more scientific, effective, and diversified comprehensive treatment plans for patients with keloids.
