Hu XY, Yang Q, Guan XY, Li JY, Wang LL, Li K, Zhang XT. Efficacy of surgical resection and ultra-reduced tension suture combined with superficial radiation in keloid treatment. World J Clin Cases 2023; 11(35): 8310-8319 [PMID: 38130623 DOI: 10.12998/wjcc.v11.i35.8310]
Corresponding Author of This Article
Xiao-Tao Zhang, MM, Chief Physician, Department of Radiation Oncology, The Affiliated Qingdao Central Hospital of Qingdao University, No. 127 Siliunan Road, Qingdao 266042, Shandong Province, China. xiaotaozhangdr@yeah.net
Research Domain of This Article
Dermatology
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Xiao-Ying Hu, Qiao Yang, Xiao-Yu Guan, Ling-Ling Wang, Kun Li, Department of Cosmetic Medicine, Qingdao Eighth People’s Hospital, Qingdao 266100, Shandong Province, China
Jin-Ying Li, Xiao-Tao Zhang, Department of Radiation Oncology, The Affiliated Qingdao Central Hospital of Qingdao University, Qingdao 266042, Shandong Province, China
Author contributions: Hu XY designed and performed the research and wrote the paper; Zhang XT designed the research and supervised the report; Yang Q, Guan XY, and Li JY organized the materials; Wang LL and Li K contributed to the analysis; All authors have approved the manuscript.
Supported byQingdao Medical Research Guidance Program Project, No. 2020-WJZD110.
Institutional review board statement: This study was reviewed and approved by the Ethics Committee of Qingdao Eighth People’s Hospital (Approval no.: QBYLL-KY-2023-013).
Informed consent statement: This retrospective study used only anonymous patient data. The patient signed an informed consent form for treatment before surgery, and according to institutional policies, informed consent for this study was waived.
Conflict-of-interest statement: All the authors declare no conflicts of interest related to this article.
Data sharing statement: The datasets used and/or analyzed during the current study are available from the corresponding author upon reasonable request.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xiao-Tao Zhang, MM, Chief Physician, Department of Radiation Oncology, The Affiliated Qingdao Central Hospital of Qingdao University, No. 127 Siliunan Road, Qingdao 266042, Shandong Province, China. xiaotaozhangdr@yeah.net
Received: November 10, 2023 Peer-review started: November 10, 2023 First decision: November 22, 2023 Revised: December 1, 2023 Accepted: December 6, 2023 Article in press: December 6, 2023 Published online: December 16, 2023 Processing time: 34 Days and 2.1 Hours
Abstract
BACKGROUND
There are many available treatment options for keloid; however, single treatments are usually less effective. Therefore, more scientifically rational and effective combined treatment methods should be sought to solve the pain associated with keloids.
AIM
To explore the efficacy and safety of surgical resection and ultra-reduced tension suture combined with superficial radiation as keloid treatment.
METHODS
Fifteen keloid patients admitted to Qingdao Eighth People's Hospital from June 2020 to January 2022 were enrolled in this retrospective analysis. All patients underwent a comprehensive treatment approach comprising surgical resection, ultra-reduced tension suture incision, and superficial radiation therapy within 24 h postoperatively. The modified Vancouver Scar Scale (mVSS) and Patient and Observer Scar Assessment Scale (POSAS) were used to evaluate the treatment effect, whereas the efficacy, adverse effects, and recurrence rate were observed according to the 12-mo follow-up after treatment.
RESULTS
The mVSS and POSAS scores at 1 and 6 mo after combination treatment decreased compared to before treatment (P < 0.001), and the overall response rate was 93.3%. Only one case recurred, yielding a 6.7% recurrence rate. The incidence of local chromour sedimentation rate in 1–3 mo after radiotherapy was 33.3% (5 patients), all subsiding after 6–9 mo, without complications, such as delayed wound healing or dermatitis.
CONCLUSION
Surgical resection, super subtraction sutures, and superficial radiotherapy are treatment methods with short courses, low recurrence rates, and good safety profiles.
Core Tip: This study utilizes the most advanced ultra-reduced tension suture technology combined with superficial radiation therapy, known as "superficial radiation therapy," to reduce the recurrence rate of keloids. Only a few reports on this combination therapy method have been reported in China. Based on the pre-and post-treatment follow-up observations, comparison of photographs, and analysis of quantitative indicators in the scar evaluation table, this combination therapy can achieve a short treatment course, low recurrence rate, and good safety profile.
