Lyu Z, Fan Y, Bai Y, Liu T, Zhong LL, Liang HF. Outcome of the efficacy of Chinese herbal medicine for functional constipation: A systematic review and meta-analysis. World J Clin Cases 2022; 10(15): 4856-4877 [PMID: 35801027 DOI: 10.12998/wjcc.v10.i15.4856]
Corresponding Author of This Article
Hui-Feng Liang, MD, PhD, Shanghai University of Traditional Chinese Medicine, No. 1200 Cai Lun Road, Shanghai 201203, China. lianghuifeng5418@shutcm.edu.cn
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Meta-Analysis
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. May 26, 2022; 10(15): 4856-4877 Published online May 26, 2022. doi: 10.12998/wjcc.v10.i15.4856
Outcome of the efficacy of Chinese herbal medicine for functional constipation: A systematic review and meta-analysis
Zipan Lyu, Yibo Fan, Yang Bai, Tao Liu, Linda LD Zhong, Hui-Feng Liang
Zipan Lyu, Yibo Fan, Teaching and Research Division, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR 99977, China
Yang Bai, Department of Cardiology, Xiyuan Hospital of China Academy of Chinese Medical Sciences, Beijing 100091, China
Tao Liu, Department of Digestive Endoscope Center, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China
Linda LD Zhong, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong 999077, China
Hui-Feng Liang, The Institute for Science, Technology and Humanities, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
Author contributions: Lyu Z and Bai Y contributed toward the concept and data analysis; Lyu Z and Fan Y contributed toward manuscript writing; Zhong LL, Liu T, and Liang HF contributed toward concept and manuscript review; In addition, Lyu Z, Fan Y and Bai Y made equal contributions; Zhong LL and Liang HF should be considered as co corresponding authors.
Supported bythe Hong Kong Chinese Medicine Development Fund (19B2/057A). The fund agency has no role in conducting the research.
Conflict-of-interest statement: The authors deny any conflict of interest.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hui-Feng Liang, MD, PhD, Shanghai University of Traditional Chinese Medicine, No. 1200 Cai Lun Road, Shanghai 201203, China. lianghuifeng5418@shutcm.edu.cn
Received: May 31, 2021 Peer-review started: May 31, 2021 First decision: June 25, 2021 Revised: July 14, 2021 Accepted: April 2, 2022 Article in press: April 2, 2022 Published online: May 26, 2022
ARTICLE HIGHLIGHTS
Research background
Well-designed and high-quality reported randomized controlled trials (RCTs) are needed to confirm more definitive conclusions in the future.
Research motivation
A firm conclusion could not be reached because of the poor quality of the included trials.
Research objectives
Chinese herbal medicine (CHM) may have potential benefits in increasing the number of bowel movements, improving stool characteristics and alleviating global symptoms in functional constipation (FC) patients.
Research methods
To evaluate the efficacy and safety of CHM on efficacy rate, global symptoms, bowel movements, and the Bristol Stool Scale score in patients with FC by summarizing current available RCTs.
Research results
This review aimed to evaluate the efficacy and safety of CHM in patients with FC.
Research conclusions
To evaluate the efficacy and safety of CHM in patients with FC.
Research perspectives
FC is a common and chronic gastrointestinal disease.
